This study is currently not recruiting participants.

Epigenetic Factors and Preterm Birth

Study on Epigenetic Factors in Preterm Birth

Not Recruiting
1 years or below
All

Brief description of study.

The purpose of this study is to better understand the molecular etiology of preterm birth, with a primary focus on the identification of epigenetic diagnostics of preterm birth susceptibility.

Eligibility of study

You may be eligible for this study if you meet the following criteria:

  • Conditions: Preterm Birth, Healthy
  • Age: 1 years or below
  • Gender: All

Inclusion Criteria

•    Cases will include infants born preterm at ≥22 and <37 weeks gestation and their biological mothers and fathers with a special interest in <32 weeks gestation.
•    Controls will include infants born full term at ≥37 weeks gestation who are similar to cases in race and gender and their biological mothers and fathers with a special interest in ≥39 weeks gestation.

Exclusion Criteria

•    Cases and Controls will exclude multiple births (i.e. twins, triplets, etc.), infant birth defects, and maternal uterine anomalies.
•    Participants who do not fluently speak, read, or understand English as they will not be able to fully interpret consent and authorization documents as well as in-depth maternal and paternal study questionnaires.

This study investigates the reasons behind preterm birth, which means a baby is born too early, before 37 weeks of pregnancy. The focus is on finding out how certain changes in genes, called epigenetic changes, might help doctors predict who is more likely to have a preterm birth. Epigenetics is a study of how your behaviors and environment can cause changes that affect the way your genes work.

Participants will be involved in procedures that include providing biological samples and completing questionnaires. These procedures help researchers understand the genetic and environmental factors that might contribute to preterm births. The study does not involve any treatment or medication.

  • Who can participate: Infants born preterm between 22 and 37 weeks, and their biological parents, can participate. Full-term infants born at 39 weeks or later, and their parents, are also eligible. Participants must speak and understand English.
  • Study details: Participants will provide biological samples and complete questionnaires to explore genetic and environmental factors related to preterm birth. No treatment or medication is involved in this study.
Updated on 19 Feb 2024. Study ID: 1901985132

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