The purpose of this study is to determine if an investigational medication is effective in treating patients with relapsed or refractory advanced breast cancer. Advanced breast cancer is a stage of cancer where the cancer has spread beyond the breast to other parts of the body. Relapsed means the cancer has returned after treatment, and refractory means it does not respond to treatment.

Participants in the study will be assigned to different study arms, which means they will receive different treatments. The study will involve regular monitoring and assessments to see how well the investigational medication works and to check for any side effects.

• Who can participate: Participants must be adults diagnosed with advanced breast cancer that is either relapsed or refractory. Additional eligibility criteria include a specific age range and health status as determined by the study guidelines.
• Study details: Participants will receive either the investigational medication or a placebo. A placebo is an inactive substance that looks like the investigational medication but does not contain any medicine.