This study is currently not recruiting participants.

Dental Plaque-Associated Systemic Inflammation in Hispanic and Caucasian Gingivitis Patients

Investigating the Impact of Dental Plaque on Systemic Inflammation

Not Recruiting
100 years or below
All
Phase N/A

Brief description of study.

The central hypotheses are that i) increased levels of dental plaque can raise the risk for low-grade systemic endotoxemia and inflammation even in the absence of clinical periodontitis, and that ii) this risk could be impacted by race.

Detailed description of study

The central hypotheses are that i) increased levels of dental plaque can raise the risk for low-grade systemic endotoxemia and inflammation even in the absence of clinical periodontitis, and that ii) this risk could be impacted by race.

Eligibility of study

You may be eligible for this study if you meet the following criteria:

  • Conditions: Gingivitis
  • Age: 100 years or below
  • Gender: All

This study investigates how increased levels of dental plaque might affect the risk of low-grade systemic endotoxemia and inflammation. Endotoxemia refers to the presence of endotoxins, which are toxins found in the outer membrane of certain bacteria, in the bloodstream. The study aims to understand if these risks occur even without clinical periodontitis, which is a severe gum infection that can lead to tooth loss and other health problems.

Participants in the study will undergo procedures to measure the levels of dental plaque and assess any associated inflammation or endotoxemia. The study will also explore if these health risks are different among people of different races to better understand any potential disparities.

  • Who can participate: The study is open to individuals of varying racial backgrounds, aged 18 to 65. Participants should have varying levels of dental plaque but should not have clinical periodontitis.
  • Study details: Participants will have their dental plaque levels measured and will undergo tests to assess systemic inflammation and endotoxemia. The study will compare these results across different racial groups.
Updated on 19 Feb 2024. Study ID: 1401360342

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