This study investigates the use of chemotherapy in combination with radiation therapy to treat tumors. Chemotherapy is a type of cancer treatment that uses drugs to destroy cancer cells, and radiation therapy uses high-energy rays to target and kill cancer cells. The focus of this study is to determine if carboplatin, a chemotherapy drug, can be safely administered alongside focal radiation therapy, which targets only the tumor area.

Participants in this study will receive both carboplatin and focal radiation therapy. The study aims to observe the effects and safety of administering these treatments together. Focal radiation therapy is designed to minimize exposure to surrounding healthy tissue by concentrating the radiation dose on the tumor itself.

• Who can participate: Participants must meet certain eligibility criteria, including age restrictions and specific health conditions. Detailed eligibility requirements will be provided to interested individuals.
• Study details: Participants will receive an investigational medication, carboplatin, in conjunction with focal radiation therapy. Focal radiation therapy targets the tumor specifically, reducing exposure to healthy tissues. A placebo, an inactive substance that looks like the investigational medicine but does not contain any medicine, is not used in this study.