E1808; A Randomized Phase II Trial of Sunitinib/Gemcitabine or Sunitinib in Advanced Renal Cell Carcinoma With Sarcomatoid Features
Investigational Treatment for Advanced Kidney Cancer
Brief description of study.
This randomized phase II clinical trial is studying giving sunitinib malate together with or without gemcitabine hydrochloride to see how well they work in treating patients with advanced kidney cancer that cannot be removed by surgery.
Detailed description of study
The purpose of this study is to evaluate the response rate to sunitinib malate with vs without gemcitabine hydrochloride in patients with advanced renal cell carcinoma with sarcomatoid features.
Eligibility of study
You may be eligible for this study if you meet the following criteria:
- Conditions: Kidney Cancer
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Age: 18 years - 100 years
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Gender: All
This study investigates the effectiveness of an investigational medication given alone or together with another substance in treating advanced kidney cancer. Advanced kidney cancer is a type of cancer that starts in the kidneys and has spread to other parts of the body. This study focuses on patients whose cancer cannot be removed by surgery and has specific characteristics known as sarcomatoid features.
Participants will receive either the investigational medication alone or with an additional substance. The study will monitor how well these treatments work in managing the cancer.
- Who can participate: Adults aged 18 and older with advanced kidney cancer that cannot be surgically removed and exhibits sarcomatoid features are eligible. Participants must meet specific health criteria and should not have received certain prior treatments.
- Study details: Participants will be randomly assigned to receive either the investigational medication alone or in combination with another substance. This assignment is random, like flipping a coin.
Interested in the study?
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