This study is currently not recruiting participants.

Vest prevention of Early Sudden death Trial (VEST) and VEST Registry

Study on Heart Health Vest

Not Recruiting
100 years or below
All
Phase N/A

Brief description of study.

The purpose of this study is to conduct a multicenter, randomized controlled trial to test the hypothesis that a non-invasive wearable automatic defibrillator vest will reduce sudden death and death due to ventricular arrhythmia without a concomitant increase in non-sudden death mortality in the first 90 days following an MI in participants with left ventricular dysfunction, and to create a registry of VEST eligible patients for long-term follow-up to determine health and utilization outcomes.

Detailed description of study

The purpose of this study is to conduct a multicenter, randomized controlled trial to test the hypothesis that a non-invasive wearable automatic defibrillator vest will reduce sudden death and death due to ventricular arrhythmia without a concomitant increase in non-sudden death mortality in the first 90 days following an MI in participants with left ventricular dysfunction, and to create a registry of VEST eligible patients for long-term follow-up to determine health and utilization outcomes.

Eligibility of study

You may be eligible for this study if you meet the following criteria:

  • Conditions: Early Sudden death
  • Age: 100 years or below
  • Gender: All

This study investigates the use of a wearable automatic defibrillator vest to reduce sudden death and death due to ventricular arrhythmia in patients who have experienced a heart attack. The study focuses on individuals with left ventricular dysfunction, a condition where the heart's left ventricle does not pump blood effectively. The purpose is to see if the vest can help without increasing other types of death within the first 90 days after a heart attack.

Participants in the study will be randomly assigned to different study arms to test the effectiveness of the wearable vest. The study will also create a registry for long-term follow-up to monitor health and usage outcomes. This will help understand the benefits and any potential risks associated with wearing the vest.

  • Who can participate: Participants must be adults who have experienced a heart attack and have left ventricular dysfunction. Specific additional eligibility criteria were not provided.
  • Study details: Participants will wear a non-invasive automatic defibrillator vest. This vest is designed to monitor heart rhythms and deliver a shock if a life-threatening irregular heartbeat is detected. An inactive substance that looks like the investigational medicine/vaccine but does not contain any medicine may be used as a placebo for comparison.
  • Study Timelines: The study will last 90 days.
Updated on 19 Feb 2024. Study ID: 1512160017

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