This study is currently not recruiting participants.

Longitudinal Assessment of Ovarian Reserve in Adolescents With Lymphoma

Study of Reproductive Hormone Levels in Young Lymphoma Patients

Not Recruiting
29 years or below
Female
Phase N/A

Brief description of study.

This clinical trial studies blood sample markers of reproductive hormones in assessing ovarian reserve in younger patients with newly diagnosed lymphomas.

Detailed description of study

The purpose of this study is to compare anti mullerian hormone (AMH), follicle stimulating hormone (FSH), and estradiol (E2) between patients at baseline and cross section of controls and again between patients at 12 months off therapy and cross section of controls; to describe the trajectory of AMH, FSH, and E2 from baseline to 12 months after completion of gonadotoxic cancer treatment; to evaluate degree of change of AMH/FSH/E2 from baseline to end of therapy in patients; and to evaluate degree of recovery of AMH/FSH/E2 from end of therapy to 12 months off therapy.

Eligibility of study

You may be eligible for this study if you meet the following criteria:

  • Conditions: lymphoma
  • Age: 29 years or below
  • Gender: Female

This study investigates the levels of certain hormones related to ovarian reserve in young patients recently diagnosed with lymphoma. Ovarian reserve refers to the capacity of the ovary to produce eggs that are capable of fertilization. The purpose of this study is to compare the levels of anti-mullerian hormone (AMH), follicle stimulating hormone (FSH), and estradiol (E2) between these patients and a group of control participants.

Participants will have their hormone levels measured at the beginning of the study, at the end of their cancer treatment, and again 12 months after completing treatment. This will help researchers understand how these hormone levels change over time, especially after undergoing cancer treatments that may affect the ovaries.

  • Who can participate: Young patients recently diagnosed with lymphoma are eligible to participate. Specific criteria include age range and health status, which will be detailed during the screening process.
  • Study details: Participants will have blood samples taken to measure hormone levels at several points during and after treatment. A placebo is not used in this study as it focuses on measuring natural hormone levels.
Updated on 19 Feb 2024. Study ID: 1306011708 (PHO-COG-FALLO

Interested in the study?

Select a study center that’s convenient for you, and get in touch with the study team.

Connect with the study team