This study is currently not recruiting participants.

A STUDY OF THE PREVENTION OF DEMINERALIZATION POTENTIAL OF AN EXPERIMENTAL MOUTH RINSE IN AN IN SITU BIOFILM MODEL

Study on the Effects of an Investigational Mouth Rinse on Enamel

Not Recruiting
100 years or below
All
Phase N/A
1 Location

Brief description of study.

The purpose of this study is to determine if an experimental sodium fluoride mouth rinse will help prevent demineralization to a greater extent in sound bovine enamel specimens compared to a sodium fluoride control mouth rinse as measured by surface microhardness following two weeks of product use in an in situ biofilm model.

Detailed description of study

The purpose of this study is to determine if an experimental sodium fluoride mouth rinse will help prevent demineralization to a greater extent in sound bovine enamel specimens compared to a sodium fluoride control mouth rinse as measured by surface microhardness following two weeks of product use in an in situ biofilm model.

Eligibility of study

You may be eligible for this study if you meet the following criteria:

  • Conditions: partial dentures
  • Age: 100 years or below
  • Gender: All

This study investigates the effects of an investigational sodium fluoride mouth rinse on preventing demineralization of enamel. Demineralization is the loss of minerals from the tooth, which can lead to cavities. The study compares the investigational rinse to a standard sodium fluoride rinse in terms of their ability to maintain the hardness of tooth enamel.

Participants will use the mouth rinses for two weeks while researchers measure changes in the enamel's surface hardness. The study uses an in situ biofilm model, which is a method that simulates the natural environment of the mouth to test the effectiveness of the mouth rinses.

  • Who can participate: Eligibility criteria include age range and specific dental health requirements. Please contact the study coordinator for detailed eligibility information.
  • Study details: Participants will be asked to use the investigational sodium fluoride mouth rinse or a control mouth rinse for two weeks. Researchers will measure the surface hardness of enamel to assess the effectiveness of the rinses.
Updated on 19 Feb 2024. Study ID: 1608155776

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