This study is currently not recruiting participants.

Diagnosis of Atypical Subtrochanteric Fractures in The Clinical Setting

Study of Atypical Femur Shaft Fractures

Not Recruiting
100 years or below
All
Phase N/A

Brief description of study.

The purpose of this study is to estimate the proportion of men and women with femur shaft fractures who have atypical fractures according to ASBMR 2013 Task Force criteria; to identify the proportion of femur shaft fractures with individual atypical femur fracture criteria; to identify clinical factors predicting the probability of a femur shaft fracture being atypical, including BMD, comorbidities, etc.; to estimate the sensitivity and positive predictive value of physicians? clinical diagnoses (based on text reports) of atypical femur fractures after the date of the first (2009) ASBMR Task Force report (published 2010), using radiologists? adjudicated results from this study as gold standards; and to compare geometric features such as cortical thickness in ratio to the diameter of the femur shaft 5 cm below the lesser trochanter, and just distal to the fracture site, between patients identified with atypical fractures and typical fracture controls.

Detailed description of study

The purpose of this study is to estimate the proportion of men and women with femur shaft fractures who have atypical fractures according to ASBMR 2013 Task Force criteria; to identify the proportion of femur shaft fractures with individual atypical femur fracture criteria; to identify clinical factors predicting the probability of a femur shaft fracture being atypical, including BMD, comorbidities, etc.; to estimate the sensitivity and positive predictive value of physicians? clinical diagnoses (based on text reports) of atypical femur fractures after the date of the first (2009) ASBMR Task Force report (published 2010), using radiologists? adjudicated results from this study as gold standards; and to compare geometric features such as cortical thickness in ratio to the diameter of the femur shaft 5 cm below the lesser trochanter, and just distal to the fracture site, between patients identified with atypical fractures and typical fracture controls.

Eligibility of study

You may be eligible for this study if you meet the following criteria:

  • Conditions: femur fracture
  • Age: 100 years or below
  • Gender: All

This study investigates femur shaft fractures in men and women to determine how many of these fractures are atypical. Atypical fractures are those that do not follow the usual pattern and have specific characteristics as outlined by the ASBMR 2013 Task Force. The study looks at factors like bone mineral density (BMD) and other health conditions to predict the likelihood of a fracture being atypical.

Participants will undergo procedures to compare the thickness of the bone's outer layer, known as cortical thickness, in relation to the bone's diameter at specific points. The study also aims to assess the accuracy of doctors' diagnoses of atypical fractures by comparing them with expert evaluations from radiologists.

  • Who can participate: Eligibility criteria are not specified in the original description.
  • Study details: Participants will have their bone structure evaluated through imaging to measure cortical thickness and other geometric features. The study will compare these measurements between those with atypical and typical femur fractures.
Updated on 19 Feb 2024. Study ID: 1401290097

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