Effect of an H1 receptor antagonist on exercise performance in hypoxia
Investigation of an Investigational Medication on Exercise Performance at Altitude
Brief description of study.
The purpose of the proposed study is to investigate if a common over the counter antihistamine will help to improve exercise performance in a low oxygen environment, like what exists at altitude.
Detailed description of study
The purpose of this study is to determine the effect of Cetirizine (Zyrtec) on exercise performance and arterial oxygenation with acute exposure to a simulated altitude.
Eligibility of study
You may be eligible for this study if you meet the following criteria:
- Conditions: healthy
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Age: 18 years - 35 years
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Gender: All
This study investigates how an over-the-counter antihistamine affects exercise performance in environments with low oxygen levels, such as high altitudes. The study aims to understand the medication's impact on physical activities when oxygen availability is reduced.
Participants will undergo tests to measure their exercise performance and oxygen levels in their blood while being exposed to conditions that mimic high altitudes. The study will compare these results to determine the effects of the antihistamine.
- Who can participate: Participants aged 18 to 65 years who are healthy and capable of exercising at high altitudes.
- Study details: Participants will be asked to perform exercise tests under simulated high-altitude conditions. They will receive either the investigational medication or a placebo. A placebo is an inactive substance that looks like the investigational medicine but does not contain any medicine.
Interested in the study?
Select a study center that’s convenient for you, and get in touch with the study team.
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