This study is currently not recruiting participants.

Development and Validation of a Gene Expression Assay to Predict the Risk of Recurrence Disease in Cutaneous Squamous Cell Carcinoma

Investigating Gene Profiles in Primary Cutaneous Squamous Cell Carcinoma (cSCC) Tumors

Not Recruiting
100 years or below
All
Phase N/A

Brief description of study.

The primary purpose of the study is to identify a gene expression and/or mutational profile that can separate primary cutaneous squamous cell carcinoma (cSCC) tumors that have high risk of recurrence compared to primary cutaneous squamous cell carcinoma (cSCC) tumors that have low risk of recurrence using a prognostic molecular test (RT-PCR and RNA sequencing).

Detailed description of study

The primary purpose of the study is to identify a gene expression and/or mutational profile that can separate primary cutaneous squamous cell carcinoma (cSCC) tumors that have high risk of recurrence compared to primary cutaneous squamous cell carcinoma (cSCC) tumors that have low risk of recurrence using a prognostic molecular test (RT-PCR and RNA sequencing).

Eligibility of study

You may be eligible for this study if you meet the following criteria:

  • Conditions: Cutaneous Squamous Cell Carcinoma
  • Age: 100 years or below
  • Gender: All

This study investigates a way to understand skin cancer called primary cutaneous squamous cell carcinoma (cSCC). The purpose is to find a specific gene pattern that can help doctors know if a tumor is likely to come back after treatment. This is done using special tests that look at the genes in the tumor, including a method called RT-PCR and another method called RNA sequencing.

Participants in this study will have their tumors tested using these methods to see how the genes are expressed. This helps researchers learn more about which tumors might be more dangerous and likely to return after treatment.

  • Who can participate: This study targets individuals diagnosed with primary cutaneous squamous cell carcinoma (cSCC).
  • Study details: Tumor samples from participants will be analyzed to identify gene expression patterns. This involves using RT-PCR, a technique to amplify DNA sequences, and RNA sequencing, which determines the sequence of RNA molecules in a sample, to understand the tumor's genetic makeup.
Updated on 19 Feb 2024. Study ID: 1708728214

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