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Found 412 ctsi-central-admin trials

A listing of ctsi-central-admin medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Study on Pre-surgical Treatment for Muscle Invasive Bladder Cancer

18 years - 100 years
All genders
This study investigates treatments for muscle invasive bladder cancer, which is a type of cancer affecting the bladder muscle. The purpose is to explore the effects of different treatments before surgery in patients who are candidates for neoadjuvant therapy. Neoadjuvant therapy is treatment given before the main treatment, which is …
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Study on Active Music Engagement (AME) Intervention for Emotional Distress in Cancer Treatment

3 years - 8 years
All genders
This study investigates how an Active Music Engagement (AME) intervention, which is an interactive, music-based play activity, can help manage emotional distress and improve health outcomes for parents and young children with cancer during treatment. The purpose is to understand the behavioral, social, and psychological factors that contribute to the …
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Investigating the Effects of Adding Investigational Medication to Chemotherapy for Prostate Cancer (PCA)

18 years - 100 years
All genders
This study investigates the effects of adding an investigational medication to the usual chemotherapy regimen for patients with prostate cancer (PCA). Prostate cancer is a disease where cancer cells form in the tissues of the prostate. The study aims to understand the positive or negative effects of this combination treatment …
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Study on Investigational Device for Biventricular Heart Failure

19 years - 75 years
All genders
The purpose of this study is to investigate if the investigational device can support individuals who are at high risk of death due to biventricular heart failure and are eligible for a heart transplant. Biventricular heart failure is a condition where both sides of the heart are not functioning properly, …
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Study on Investigational Medication for Neurofibromatosis Type 1

2 years - 100 years
All genders
This study investigates the use of an investigational medication for patients with neurofibromatosis type 1 (NF1), a genetic disorder that causes tumors to form on nerve tissue. The study focuses on patients with inoperable, progressive, or symptomatic plexiform neurofibromas (PN), which are complex tumors associated with NF1. These patients have …
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Investigating the Effect of an Investigational Medication on ALS Symptoms

18 years - 75 years
All genders
This study investigates the effect of an investigational medication on adults with Amyotrophic Lateral Sclerosis (ALS). ALS is a condition that affects nerve cells in the brain and spinal cord, leading to loss of muscle control. The purpose of this study is to see if adding the investigational medication to …
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Investigating Hormone-Blocking Treatment Interruption and Breast Cancer Recurrence

18 years - 42 years
Female
This study investigates if taking a break from endocrine therapy to allow pregnancy affects the risk of breast cancer coming back. It focuses on young women who have had early breast cancer and are interested in becoming pregnant. Endocrine therapy involves using medicines that block certain hormones to slow or …
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Investigating the Safety and Tolerability of an Investigational Medication in Relapsing-Remitting Multiple Sclerosis (RRMS)

18 years - 100 years
All genders
This study investigates the safety and tolerability of an investigational medication in individuals with Relapsing-Remitting Multiple Sclerosis (RRMS). RRMS is a type of multiple sclerosis characterized by periods of new or increasing neurological symptoms followed by periods of partial or complete recovery. The study focuses on participants who have not …
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Investigation of Treatments for Metastatic Castration-Resistant Prostate Cancer with DNA Repair Defects

18 years - 100 years
Male
This study investigates treatments for men with metastatic castration-resistant prostate cancer (mCRPC) who have DNA repair defects. The purpose is to assess the effectiveness of two drugs that are approved by the US FDA, both individually and in combination. Metastatic castration-resistant prostate cancer is a type of prostate cancer that …
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Investigating the Relationship Between Sensory Stimuli and Alcohol Use Behavior

21 years - 55 years
All genders
This study investigates the connection between how people respond to visual and auditory stimuli and their alcohol-related behaviors. Alcohol use disorders can be hard to treat because individuals may not react to the negative effects on their health and life. Researchers aim to understand how people who continue to drink …
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