A listing of ctsi-central-admin medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
This study investigates the effects of imatinib therapy on children with neurofibromatosis type 1 (NF1) who have airway-related plexiform neurofibromas. Plexiform neurofibromas are a type of tumor that can grow in various parts of the body, including the airway. The study aims to see if these specific tumors are more …
The purpose of this study is to find out if music play activities can decrease distress and improve the quality of life for parents and young children during stem cell transplants for cancer. Stem cell transplant is a procedure used to replace damaged or destroyed bone marrow with healthy bone …
This study investigates treatments for muscle invasive bladder cancer, which is a type of cancer affecting the bladder muscle. The purpose is to explore the effects of different treatments before surgery in patients who are candidates for neoadjuvant therapy. Neoadjuvant therapy is treatment given before the main treatment, which is …
This study investigates the genetic factors related to aortopathy and aortic valve disease. Aortopathy refers to conditions affecting the aorta, the main artery of the body, while aortic valve disease affects the valve that controls blood flow from the heart to the aorta. The study aims to identify genes that …
This study investigates how an Active Music Engagement (AME) intervention, which is an interactive, music-based play activity, can help manage emotional distress and improve health outcomes for parents and young children with cancer during treatment. The purpose is to understand the behavioral, social, and psychological factors that contribute to the …
This study investigates a blood test called a "liquid biopsy" to find cancer cells in the blood of bladder cancer patients. Bladder cancer is a disease where cells in the bladder grow uncontrollably. This study aims to see if the test can reliably detect these cancer cells.The study uses a …
This study investigates an investigational medication in children with recurrent or refractory solid tumors, including tumors in the central nervous system (CNS). The purpose is to determine the highest dose that children can tolerate. The study will also look into how the medication affects the body, its side effects, and …
This study investigates the safety of an investigational medication in children who have solid tumors that have returned or are not responding to treatment. Solid tumors are abnormal masses of tissue that can occur in various parts of the body, including the brain and spinal cord, which are part of …
This study investigates the safety of two investigational medications in treating adults with liver cancer that cannot be removed by surgery. The medications are being tested alone and in combination to evaluate their effects on liver cancer, also known as hepatocellular carcinoma.Participants in this study will undergo treatment with either …
This study investigates the safety and feasibility of using an investigational treatment involving allogeneic human mesenchymal stem cells (allo-MSCs) for cancer survivors who have heart problems. These heart problems are a result of a condition called anthracycline-induced cardiomyopathy (AIC), which happens when certain cancer treatments affect the heart's ability to …