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Found 204 Neoplasms trials

A listing of Neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Investigating Hormone-Blocking Treatment Interruption and Breast Cancer Recurrence

18 - 42
Female
This study investigates if taking a break from endocrine therapy to allow pregnancy affects the risk of breast cancer coming back. It focuses on young women who have had early breast cancer and are interested in becoming pregnant. Endocrine therapy involves using medicines that block certain hormones to slow or …
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Study on Breast Cancer Screening Methods

45 - 74
Female
This study investigates the effectiveness of two methods for breast cancer screening: digital tomosynthesis mammography and digital mammography. The purpose of this study is to compare how often advanced breast cancer occurs in participants who are screened using these two methods over a period of 4.5 years. Digital tomosynthesis mammography …
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Investigating the Effects of Chemotherapy on Fertility in Osteosarcoma Survivors

18 - 50
Male
This study investigates the effects of chemotherapy on fertility in male osteosarcoma survivors. Osteosarcoma is a type of bone cancer, and this study aims to understand if the chemotherapy drugs cisplatin, with or without ifosfamide, affect fertility compared to males without a history of cancer. The study also examines if …
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Investigating the Effectiveness of an Investigational Medication in Recurrent Non-Muscle Invasive Bladder Cancer

18 - 100
All genders
This study investigates the effectiveness of an investigational medication for patients with non-muscle invasive bladder cancer that has returned and not responded to previous treatment. Non-muscle invasive bladder cancer is a type of cancer that affects the inner lining of the bladder but does not penetrate the bladder muscle. The …
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Study on the Effects of an Investigational Medication Combination in Skin Cancer (Melanoma) Patients

18 - 100
All genders
This study investigates the effects of a combination of investigational medications in patients with melanoma. Melanoma is a type of skin cancer that can spread to other parts of the body. The purpose of this study is to evaluate how well this combination works in patients who have already tried …
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Investigating Radiation Therapy with or without Investigational Medication for Inflammatory Breast Cancer

18 - 100
All genders
This study investigates the effectiveness of radiation therapy with or without an investigational medication in treating patients with inflammatory breast cancer. Inflammatory breast cancer is a rare and aggressive form of breast cancer that spreads quickly. Radiation therapy uses high-energy x-rays to kill cancer cells and shrink tumors. The investigational …
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Investigating the Use of Investigational Medications in Breast Cancer Treatment

18 - 100
All genders
Phase 2
This study investigates whether adding investigational medications to a treatment regimen can improve progression-free survival in patients with advanced HER2-positive breast cancer. HER2-positive breast cancer is a type of breast cancer that tests positive for a protein called human epidermal growth factor receptor 2, which promotes the growth of cancer …
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Study on Investigational Medication for Triple-Negative Breast Cancer

18 - 100
All genders
This study investigates the effects of an investigational medication in patients with triple-negative breast cancer (TNBC). Triple-negative breast cancer is a type of cancer that does not have estrogen receptors, progesterone receptors, or HER2 protein, which are common targets in other breast cancer treatments. The purpose of this study is …
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Cognitive Changes in Older Women Post Breast Cancer Treatment

60 - 100
Female
This study investigates how systemic therapy affects cognitive functioning in older women who have undergone breast cancer treatment. Cognitive functioning refers to mental processes like thinking, learning, memory, and problem-solving. Researchers aim to understand if and how these treatments impact these abilities.Participants in this study will undergo various assessments to …
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Investigating Weight Loss to Prevent Breast Cancer from Returning

18 - 100
Female
This study investigates whether weight loss can prevent breast cancer from coming back in overweight and obese women. Breast cancer is a disease where cells in the breast grow out of control. The study involves women who have early-stage breast cancer and compares two different approaches to weight loss: a …
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