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Found 204 Neoplasms trials

A listing of Neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Study on Investigational Approaches for Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia

2 - 21
All genders
This study investigates treatments for Philadelphia chromosome positive acute lymphoblastic leukemia (ALL), a type of cancer affecting the blood and bone marrow. The purpose of this study is to examine the effectiveness of combining an investigational medication with different chemotherapy approaches to improve disease-free survival in children with standard risk …
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Investigational Treatment for Blood Cancer in Down Syndrome

3 or below
All genders
This study investigates response-based chemotherapy for treating newly diagnosed acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) in younger patients with Down syndrome. Down syndrome is a genetic condition caused by an extra chromosome 21, also known as trisomy 21. The study aims to understand how different chemotherapy drugs can …
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Research Study: Investigating Combination Chemotherapy for High-Risk Acute Lymphoblastic Leukemia

1 - 30
All genders
This study investigates how well combination chemotherapy works in treating young patients with acute lymphoblastic leukemia (ALL), a type of cancer that affects the blood and bone marrow and is likely to return or spread. The purpose is to see if a specific treatment approach can improve disease-free survival in …
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Study Comparing Treatments for Relapsed B-cell Acute Lymphoblastic Leukemia

1 - 30
All genders
This study investigates treatments for B-cell acute lymphoblastic leukemia (B-ALL) that has returned after improvement, also known as relapsed B-ALL. The purpose is to compare two treatments: a standard combination of chemotherapy and an investigational medication called blinatumomab. B-ALL is a type of cancer affecting white blood cells, and relapsed …
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Investigation of an investigational medication for treating pediatric and young adult leukemia and lymphoma

1 - 30
All genders
This study investigates the effectiveness of an investigational medication for treating children and young adults with acute lymphoblastic leukemia or lymphoblastic lymphoma. Acute lymphoblastic leukemia is a type of cancer that affects the blood and bone marrow, while lymphoblastic lymphoma is a similar cancer affecting lymph nodes. The study aims …
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Investigational Treatment Access for Blood Cancer Patients

100 or below
All genders
This study investigates the use of an investigational treatment for patients with certain types of blood cancer, specifically acute lymphoblastic leukemia (ALL) and diffuse large B-cell lymphoma (DLBCL). These patients have a special need due to their leukapheresis product not meeting standard specifications. Leukapheresis is a procedure to collect blood …
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Investigating Safe Doses for Post-Transplant Treatment

18 - 100
All genders
This study investigates the safe dosage levels of an investigational medication alone and in combination with another investigational medication after a type of stem cell transplant. It focuses on patients with blood cancers like acute myeloid leukemia and myelodysplastic disorders. The study aims to understand the effects of these medications …
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Study on Blood Sample Collection in Patients Undergoing Stem Cell Transplantation

18 or below
All genders
The purpose of this study is to collect blood specimens and data from patients undergoing a stem cell transplant. Stem cell transplants are procedures where patients receive blood-forming stem cells to replace damaged or diseased bone marrow. This study aims to gather information from patients who have certain conditions or …
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Investigating Chemotherapy with or without investigational medication for T-Cell Leukemia and Lymphoma

2 - 30
All genders
This study investigates the effectiveness of combination chemotherapy with or without an investigational medication in patients with newly diagnosed T-cell acute lymphoblastic leukemia (T-ALL) or stage II-IV T-cell lymphoblastic lymphoma (T-LLy). T-cell acute lymphoblastic leukemia is a type of cancer that affects the blood and bone marrow, while T-cell lymphoblastic …
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Investigating Overall Survival in Myelodysplastic Syndromes (MDS) Patients Using Investigational Medication

18 - 81
All genders
This study investigates the overall survival of patients with Myelodysplastic Syndromes (MDS) who have not responded to previous treatments. MDS is a group of disorders caused by poorly formed or dysfunctional blood cells. The study compares two groups: one receiving an investigational medication and the other receiving treatments chosen by …
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