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Found 9 Acute Myeloid Leukemia trials

A listing of Acute Myeloid Leukemia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Clinical Trial on Investigational Treatment for Hypertension

20 - 70
Female
Who can participate: Adults aged 18 to 65 with a diagnosis of hypertension, who are otherwise healthy and not currently on antihypertensive medication, may be eligible to participate. Participants must not have a history of cardiovascular events.Study details: Participants will be randomly assigned to receive either the investigational treatment or …
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Investigational Treatment for Blood Cancer in Down Syndrome

3 or below
All genders
This study investigates response-based chemotherapy for treating newly diagnosed acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) in younger patients with Down syndrome. Down syndrome is a genetic condition caused by an extra chromosome 21, also known as trisomy 21. The study aims to understand how different chemotherapy drugs can …
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Investigating Priming Before Chemotherapy in Children with AML

22 or below
All genders
This study investigates the safety and effectiveness of using DNA methyltransferase inhibitors (DMTi) before chemotherapy in treating children with acute myeloid leukemia (AML). DNA methyltransferase inhibitors are substances that may help in modifying the genes' activity without changing the DNA sequence itself. The purpose is to see if these inhibitors …
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Investigating Survival in Patients Based on Donor Match Likelihood

100 or below
All genders
This study investigates the survival outcomes of patients with certain blood disorders who are likely or unlikely to find a matched unrelated donor (MUD) for a transplant. The conditions include acute myeloid leukemia (AML), acute lymphoblastic leukemia (ALL), myelodysplastic syndromes (MDS), non-Hodgkin lymphoma (NHL), Hodgkin lymphoma (HL), aplastic anemia (AA), …
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Investigational Medication for Acute Myeloid Leukemia with FLT3 Mutation

18 - 60
All genders
This study investigates the treatment of acute myeloid leukemia (AML) in patients with a specific genetic change called FLT3 mutation. The purpose is to compare two investigational medications given after initial and follow-up chemotherapy, as well as after bone marrow transplant, to see which is more effective in extending the …
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Study on Reducing Acute Myeloid Leukemia (AML) Recurrence with Additional Treatment

60 - 100
All genders
This study investigates whether adding an investigational medication to the usual treatment can lower the chances of acute myeloid leukemia (AML) returning or worsening. AML is a type of cancer that affects the blood and bone marrow, where blood cells are made. The study aims to find out if the …
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Investigational Medication for Acute Myeloid Leukemia

18 - 100
All genders
Phase 1/2
This study investigates the safety and effectiveness of combining two investigational medications for treating acute myeloid leukemia (AML). AML is a type of cancer that affects the blood and bone marrow. The study will look at how many patients respond to treatment with these investigational medications.Participants will receive the investigational …
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Investigating Total Marrow Irradiation for Stem Cell Transplant Preparation

18 - 65
All genders
This study investigates a new type of radiation therapy called total marrow irradiation (TMI) for patients undergoing allogeneic hematopoietic stem cell transplantation (Allo-HSCT). It aims to find the most effective dose of TMI when used with a chemotherapy drug called fludarabine. This combination is used to prepare patients for the …
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Investigating Safe Doses for Post-Transplant Treatment

18 - 100
All genders
This study investigates the safe dosage levels of an investigational medication alone and in combination with another investigational medication after a type of stem cell transplant. It focuses on patients with blood cancers like acute myeloid leukemia and myelodysplastic disorders. The study aims to understand the effects of these medications …
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