Neural Response to Risky Decision Making in Youth at High Risk for Substance Use Disorders and HIV

Risky Decision-Making and Brain Development in Children

Neural Response to Risky Decision Making in Youth at High Risk for Substance Use Disorders and HIV
Recruiting
11 years - 12 years
All
Phase N/A
1 Location

Brief description of study.

The purpose of this study is to understand more about what leads some children to develop drug addiction as they grow older.

Detailed description of study

The purpose of this study is to understand more about what leads some children to make potentially dangerous, risky decisions as they grow older.  We want to carefully study their behavior and scan their brains in a brain scanner (magnetic resonance imager or MRI). We will compare the children at risk with a group of typically developing children to understand more about the brain’s basis for making risky decisions. 
Seeking children 11-12 years old with or without:
   - ADHD
   - Behavioral Issues
   

Participants will be paid for their participation.

Eligibility of study

You may be eligible for this study if you meet the following criteria:

  • Conditions: ODD,Attention Deficit Hyperactivity Disorder,ADHD,Conduct Disorder,Oppositional Defiance Disorder,Healthy,Substance Use Disorder,SUD,substance use,substance abuse,addiction,youth,adolescent,kid,kids,child,children,pediatric,riley,HIV
  • Age: 11 years - 12 years
  • Gender: All

Inclusion Criteria
ADHD + ODD or CD diagnoses
Healthy
Right Handed
Exclusion Criteria
Family history of SUDs in 1st or 2nd degree relatives
Lifetime history of bipolar disorder, psychotic symptoms, pervasive development disorders or SUDs
Current major depressive disorder
Current psychopharmacologic treatment other than psychostimulants
History of neurological problems
Active or debilitating medical conditions
Active maternal substance use disorder during pregnancy
Claustrophobia
Pregnant
MRI contraindications
Left Handed

Updated on 19 Feb 2024. Study ID: 1603169831

This study investigates why some children develop drug addiction as they grow older. It aims to understand what leads to risky decision-making in children by studying their behavior and scanning their brains using a magnetic resonance imager (MRI). Researchers will compare children at risk with typically developing peers to learn more about the brain's role in these decisions.

Participants will undergo brain scans using MRI, which is a machine that takes pictures of the brain. The study will include children with conditions like ADHD and those without, to compare their brain activity. Participants will be compensated for their involvement in the study.

  • Who can participate: Children aged 11-12 years, both with and without ADHD or behavioral issues, are eligible. Participants must be right-handed and healthy, without a family history of substance use disorders or certain mental health conditions.
  • Study details: Participants will have their brains scanned using an MRI, which takes detailed images of the brain. They will not receive any medication and will be compensated for their participation.

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