CT-Based Muscle Changes in a Retrospective Cohort of Patients

Investigating Muscle Deterioration After Traumatic Injury

Enrolling By Invitation
18 years - 55 years
All

Brief description of study.

The purpose of this study is that patients who have muscle deterioration after experiencing a traumatic injury will have worse long term outcomes than patients who do not have muscle deterioration.

Detailed description of study

We plan to prove that using the change in muscle mass on serial CT scans can be used as a tool to identify patients who are at risk of a poor long term outcome and intervene in their care through aggressive nutritional and rehabilitation support in hopes of improving their recovery.

Eligibility of study

You may be eligible for this study if you meet the following criteria:

  • Conditions: Traumatic injury, Muscle deterioration
  • Age: 18 years - 55 years
  • Gender: All

Inclusion Criteria

Polytraumatized patients with ISS scores >18 from January 1, 2013-December 31, 2017
Patients with two or more CT scans of the abdomen and pelvis within a 6 month period
Patients who respond to the phone call/mail surveys to obtain survey data

Exclusion Criteria

Patients with ISS scores <18
Patients with less than two CT scans of the abdomen and pelvis
People who fail follow up or who fail to respond to phone calls/mail surveys.

This study investigates the impact of muscle deterioration on patients who have experienced a traumatic injury. Muscle deterioration refers to the loss of muscle mass, which can happen after a severe injury. The purpose of this study is to see if changes in muscle mass, observed through CT scans, can help identify patients at risk for worse long-term outcomes.

Participants will undergo CT scans to monitor changes in muscle mass. The study aims to use these scans to identify patients who might need additional nutritional and rehabilitation support to improve their recovery. CT scans are detailed imaging tests that help doctors see inside the body.

  • Who can participate: Participants must be polytraumatized patients with an Injury Severity Score (ISS) greater than 18 and have had two or more CT scans of the abdomen and pelvis within a 6-month period. They must also be able to respond to phone calls or mail surveys.
  • Study details: Participants will have their muscle mass monitored through CT scans. They may receive additional nutritional and rehabilitation support if identified as at risk. A placebo is not involved in this study.
Updated on 19 Feb 2024. Study ID: 1811363979

Interested in the study?

study is selecting its participants from a population, or group of people, decided on by the researchers in advance.

Contact a study center.