Role of the Sympathetic Nervous System in Rosacea

Investigating the Relationship Between Rosacea and the Nervous System

Recruiting
18 years - 45 years
All
1 Location

Brief description of study.

The purpose of this research study is to better understand rosacea and its possible relation to the nervous system.

Detailed description of study

Researchers in the Department of Physical Therapy of Indiana University at IUPUI are seeking healthy men and nonpregnant/non-lactating women between the ages of 18-45 years old to participate in a research study investigating the relationship between rosacea and the sympathetic nervous system.  We are recruiting both persons who have been diagnosed with subtype 1 rosacea and healthy control participants.  Participation involves pharmaceutical agents applied to the skin.  After completing 2 screening visits which will each take about 30 minutes, participants will complete 2 sessions which each last about 3-4.5 hours.  Minor financial compensation is provided for participating in these studies.

Eligibility of study

You may be eligible for this study if you meet the following criteria:

  • Conditions: Healthy,Rosacea
  • Age: 18 years - 45 years
  • Gender: All

Inclusion Criteria

Otherwise healthy males and non-pregnant/non-lactating females ages 18-45 years with mild to moderate erythematotelangiectatic rosacea, as well as age-sex matched healthy control subjects. Subjects will be apparently healthy as assessed through a pre-screening phone conversation and health history and physical exam.

Exclusion Criteria

Neurological, cardiovascular, respiratory, metabolic, muscular, or other dermatological disorders.
Current history of alcohol and/or drug abuse.
Known allergies or hypersensitivities to medications/drugs that are used in the protocol.
Current smoking or regular smoking within the last 2 years.
Medications or supplements which are known to affect neural, cardiovascular, or muscular responses.

Updated on 19 Feb 2024. Study ID: 1808016098

This study investigates the relationship between rosacea, a skin condition causing redness and visible blood vessels, and the sympathetic nervous system, which is part of the nervous system that controls the body's 'fight or flight' response. Researchers at Indiana University are looking at how rosacea might be linked to this part of the nervous system.

Participants will have pharmaceutical agents applied to their skin. The study includes two screening visits, each lasting about 30 minutes, followed by two sessions that each last between 3 to 4.5 hours. Minor financial compensation is provided for participation.

  • Who can participate: Healthy men and non-pregnant/non-lactating women aged 18 to 45 years with mild to moderate rosacea can participate. Healthy individuals without rosacea are also needed as control subjects.
  • Study details: Participants will have investigational pharmaceutical agents applied to their skin. The study involves two screening visits and two main sessions.
  • Study Visits: The study requires 4 visits.

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