Glycosylation of Urinary Exosomes in Prostate and Urothelial Carcinoma
Study on Urinary Biomarkers for Prostate and Bladder Cancer
Brief description of study.
The purpose of this study is to collect a urine sample from patients with prostate and urothelial (bladder) cancer and healthy volunteers who do not have cancer, so that researchers can perform studies on microcellular structures called exosomes that may lead to a new type of urinary biomarker test for prostate and urothelial cancer.
Detailed description of study
The purpose of this study is to collect a urine sample from patients with prostate and urothelial cancer and healthy volunteers who do not have cancer, so that researchers can perform studies on microcellular structures called exosomes that may lead to a new type of urinary biomarker test for prostate and urothelial cancer.
Eligibility of study
You may be eligible for this study if you meet the following criteria:
- Conditions: urothelial cancer,prostate cancer,bladder cancer,healthy,carcinoma,cancer,oncology
-
Age: 18 years - 100 years
-
Gender: Male
Inclusion Criteria
Histologically confirmed prostate or urothelial carcinoma
Localized disease
No neoadjuvant chemotherapy for disease
Healthy volunteers must not have prostate or urothelial cancer
Exclusion Criteria
Concurrent disease or condition that would make the subject inappropriate for study participation or any serious medical or psychiatric disorder that would interfere with the subject's safety
Dementia, altered mental status, or any psychiatric condition that would prohibit the understanding or rendering of informed consent
This study investigates the potential of using urine samples to find new ways to detect prostate and bladder cancer. The purpose of this study is to collect urine samples from both patients with these cancers and healthy volunteers. Researchers will study tiny structures in the urine called exosomes, which might help in creating a new test for these cancers.
Participants in this study will be required to provide a urine sample. No payment will be given for participation. Exosomes are small particles found in urine that can carry information about diseases, and studying them may help in developing new tests.
- Who can participate: Adults with confirmed prostate or bladder cancer and healthy individuals without these cancers can participate. Participants with localized disease are eligible, but those who have received chemotherapy for their cancer are not. Healthy volunteers must not have prostate or bladder cancer.
- Study details: Participants will provide a urine sample for research purposes. No compensation is provided for participation.