This study is currently not recruiting participants.

Sympathetic Nerve Activity in Amyloid Polyneuropathy

Research Study on Skin Nerve Response to Stress in Amyloidosis

Not Recruiting
18 years - 90 years
All
1 Location

Brief description of study.

The purpose of this study is use skin nerve activity to compare the response of the nervous system to stress within the nerves of the skin that may not be noticed in patients with transthyretin amyloidosis versus volunteers without amyloidosis.

Eligibility of study

You may be eligible for this study if you meet the following criteria:

  • Conditions: Amyloid Polyneuropathy, Healthy, transthyretin amyloidosis
  • Age: 18 years - 90 years
  • Gender: All

Inclusion Criteria

History of amyloidosis

Age and gender matched healthy control

Exclusion Criteria

History of type 1 or type 2 diabetes and neuropathy

Patients who are pacemaker dependent

Women who are know to be pregnant

People with a history of allergy to ECG electrodes, adhesive tape, nylon or latex

History of AMyloidosis

This study investigates how the nervous system in the skin responds to stress in patients with transthyretin amyloidosis compared to healthy volunteers. Transthyretin amyloidosis is a condition where abnormal protein builds up in the body, affecting nerves and organs.

Participants will undergo procedures to measure nerve activity in the skin. This involves using small sensors that attach to the skin to record nerve signals.

  • Who can participate: Adults with a history of amyloidosis and healthy controls may participate.
  • Study details: Participants will have their skin nerve activity measured using sensors. These sensors are placed on the skin to record how nerves respond to stress.
Updated on 19 Feb 2024. Study ID: 1812679396

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