Building a Biobank from Muscle Tissue for Research Purposes

Investigation of Muscle Samples for Musculoskeletal Health Research

Recruiting
18 years - 100 years
All
1 Location

Brief description of study.

The purpose of this study is to collect muscle samples and information from individuals for the Indiana Center for Musculoskeletal Health Clinical Research Core Biobank.

Eligibility of study

You may be eligible for this study if you meet the following criteria:

  • Conditions: Healthy
  • Age: 18 years - 100 years
  • Gender: All

Inclusion Criteria: 

  • ≥ 18 years of age  
  • Able to comprehend and willing to sign an Informed Consent Statement (ICS).
  • Body Mass Index ≤ 38.
  • Participant has not received treatment with any medications with increased bleeding risk (NSAID, Aspirin) within 1 week prior to the muscle biopsy procedure.  Acetaminophen may be used.

Exclusion Criteria:

  • Participant is known to be HIV or Hepatitis B or C positive.
  • Participant has received treatment with NSAID or Aspirin within one week, or warfarin or direct oral anticoagulants (Eliquis, Pradaxa, Xarelto, and Savaysa) within 30 days prior to muscle biopsy procedure.
  • Per self-report, any acute or chronic condition that, in the opinion of the Principal Investigator, would limit the procedure participant’s ability to complete and/or participate in this clinical procedure or could influence the biopsy procedure results.

Updated on 19 Feb 2024. Study ID: 1905097984

This study investigates the collection of muscle samples to support research on musculoskeletal health. Musculoskeletal health involves the muscles, bones, and joints that help us move and perform daily activities. The study aims to gather these samples for the Indiana Center for Musculoskeletal Health Clinical Research Core Biobank, which is a collection of biological samples used for scientific research.

Participants will undergo a muscle biopsy, which involves taking a small sample of muscle tissue for study. Before the procedure, participants must not take certain medications that can increase bleeding risk, such as NSAIDs (non-steroidal anti-inflammatory drugs) and aspirin. Acetaminophen, a common pain reliever, is allowed.

  • Who can participate: Adults aged 18 and older with a Body Mass Index of 38 or less can participate. They must understand and sign an Informed Consent Statement and avoid medications that increase bleeding risk a week before the biopsy.
  • Study details: Participants will provide muscle samples through a biopsy procedure, involving the collection of a small piece of muscle tissue. Avoiding medications like NSAIDs and aspirin before the procedure is important to reduce bleeding risk.

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