Efficacy of tDCS for improving gait in HD

Study on the Effects of Transcranial Stimulation (a method to apply a small electrical current to the brain) on Gait and Brain Excitability

Recruiting
18 years - 80 years
All
Phase N/A
1 Location

Brief description of study.

The purpose of this study is to examine the effect of transcranial direct current (tDCS) on gait and brain excitability during rest and with a weak voluntary contraction of a leg muscle.

Detailed description of study

The purpose of this study is to investigate the potential of transcranial current stimulation to improve gait and brain excitability in HD patient and healthy controls.

This study takes place in Bloomington, IN.

Participants will be compensated for their participation.

Eligibility of study

You may be eligible for this study if you meet the following criteria:

  • Conditions: healthy,Huntington's disease
  • Age: 18 years - 80 years
  • Gender: All

Inclusion Criteria
Able to walk at a self-selected speed for up to 25 minutes
Exclusion Criteria
Any neurological disorders
Family history of Huntington's disease
Heart disease
Respiratory disease
CNS surgery or injury
Seizures
Stroke
Orthopedic or pain conditions
Pregnancy
Uncontrolled hypertension
Cochlear implants, implanted neurostimulator, pace maker
Severe vision, hearing, or balance condition(s)
Diabetes
Tinnitus
Intracardiac line or medical infusion devices
Skin diseases affecting the scalp
Mental implants
Frequent severe headaches

Updated on 19 Feb 2024. Study ID: 1610700867

This study investigates the effects of transcranial direct current stimulation (tDCS) on walking ability and brain activity. Transcranial direct current stimulation is a way to send a small electrical current to the brain through the scalp. The study will look at how this stimulation affects people with Huntington's disease and those without the condition.

Participants will undergo procedures involving tDCS while resting and while making a gentle effort to move a leg muscle. The goal is to see how this affects their walking and brain activity. The study will compare results between healthy individuals and those with Huntington's disease.

  • Who can participate: Participants must be able to walk at their own speed for up to 25 minutes. Individuals with neurological disorders, a family history of Huntington's disease, or certain medical conditions like heart or respiratory disease cannot participate. Additional exclusion criteria include CNS surgery, seizures, stroke, orthopedic conditions, and pregnancy.
  • Study details: Participants will receive transcranial direct current stimulation and may be asked to perform simple tasks.

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