Predicting Progression of Developing Myeloma in a High Risk-Screened Population (PROMISE)

Investigation of Early Warning Signs for Blood Cancer Risk

Predicting Progression of Developing Myeloma in a High Risk-Screened Population (PROMISE)
Recruiting
40 years - 75 years
All
Phase N/A
1 Location

Brief description of study.

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The PROMISE study is the first study to test healthy people who may be at risk for early warnings signs of a blood cancer called multiple myeloma. 

Normal 0 false false false EN-US X-NONE X-NONE Multiple myeloma is a type of blood cancer that occurs in the bone marrow.  Before a person develops multiple myeloma, their marrow begins to make abnormal cells and proteins, which can be an early warning sign of the disease.

We're inviting qualifying adults with higher risks for multiple myeloma to participate in a screening study for early warning signs of the disease.
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We will further study people who test positive for these early warning signs of multiple myeloma so that we can learn how to prevent them from developing into cancer. 
 
Your participation may help researchers find new ways to prevent and treat blood cancer.
 

Detailed description of study

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Normal 0 false false false EN-US X-NONE X-NONE How To Join and Get Screened for Free:
 
1.     Take a short survey and decide whether to go to the next step.
 
2.     Once you have completed the enrollment and are qualified for a free screening, we will send a collection kit to you at no cost.
 
3.     When the kit arrives, it will contain instructions for how to schedule your free screening at a Quest Diagnostics lab near you where they will collect a small amount of blood. 
 
4.     We will check your blood sample for certain proteins that we call “precursor conditions for multiple myeloma.
 
5.     We will notify all participants of their results. 
 
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Please take our survey to see if you qualify: PROMISE Eligibility Questionnaire 
 
 
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This study aims to find new ways to prevent and treat blood cancer.

Your participation may help prevent multiple myeloma in future generations.

For more information, please visit the PROMISE study website: https://www.enroll.promisestudy.org/

Eligibility of study

You may be eligible for this study if you meet the following criteria:

  • Conditions: healthy,cancer,multiple mylemoa,myeloma,MGUS,cancer screening,smoldering multiple myeloma,monoclonal gammopathy of undetermined significance,waldentrom macroglobulinemia
  • Age: 40 years - 75 years
  • Gender: All

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Two groups of adults, age 40-75, qualify for a free screening:
 
1.) African Americans
 
AND / OR
 
2.) People of Any Race Who Have a Parent, Sibling, or Child with:
 
Multiple myeloma OR one of these related conditions:
 
·       Monoclonal Gammopathy of Undetermined Significance (MGUS)
 
·       Smoldering Multiple Myeloma
 
·       Waldenström Macroglobulinemia
 

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Please take our survey to see if you qualify: PROMISE Eligibility Questionnaire 
 
 

This study investigates early warning signs of a blood cancer called multiple myeloma. Multiple myeloma is a type of cancer that begins in the bone marrow, where blood cells are made. Before developing multiple myeloma, a person's bone marrow might start producing abnormal cells and proteins, which can signal the onset of the disease.

The study involves a screening process for individuals at higher risk of developing multiple myeloma. Participants will first take a survey to determine eligibility. Those who qualify will receive a collection kit to schedule a free screening at a local lab. The lab will collect a small blood sample to check for proteins that indicate precursor conditions for multiple myeloma. All participants will be notified of their results.

  • Who can participate: Adults aged 40-75 who are African American or have a family member with multiple myeloma or related conditions like MGUS, Smoldering Multiple Myeloma, or Waldenström Macroglobulinemia are eligible.
  • Study details: Participants will take a survey to see if they qualify, and if eligible, receive a collection kit for a lab screening. The lab will collect a small blood sample to test for precursor conditions.
Updated on 19 Feb 2024. Study ID: 18-370

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