Human Alcohol Seeking Despite Aversion

Investigating the Relationship Between Sensory Stimuli and Alcohol Use Behavior

Recruiting
21 years - 55 years
All
Phase N/A
1 Location

Brief description of study.

The purpose of this study is to determine the relationship between the response to visual (images) and/or auditory (sound) stimuli and alcohol related behavior.

Detailed description of study

Severe alcohol use disorders are extremely difficult to treat. This may be in part because the individual is no longer responding to the negative consequences of drinking on his or her health, family and social life, and employment. An objective laboratory measure of aversion resistant drinking (ARD) would facilitate a better understanding of the mechanisms of disease progression.
We propose to test a laboratory measure of alcohol seeking despite aversion (SDA) that may be used as an early marker of ARD in humans. Our preliminary data have shown that behavior in the SDA model is related to lifetime alcohol exposure and to alcohol use disorder (AUD) risk factors and phenotypes, and reflects alterations in brain function.
Participants will be paid for their participation.

Eligibility of study

You may be eligible for this study if you meet the following criteria:

  • Conditions: Healthy
  • Age: 21 years - 55 years
  • Gender: All

Inclusion Criteria
Alcohol drinker

Updated on 19 Feb 2024. Study ID: 1709318986

This study investigates the connection between how people respond to visual and auditory stimuli and their alcohol-related behaviors. Alcohol use disorders can be hard to treat because individuals may not react to the negative effects on their health and life. Researchers aim to understand how people who continue to drink despite negative consequences behave.

Participants will be involved in procedures that test their response to certain laboratory measures related to alcohol-seeking behavior. These measures may help identify early signs of alcohol-related disorders and changes in brain function. Participants will receive compensation for their time.

  • Who can participate: Adults who drink alcohol are eligible to participate in this study.
  • Study details: Participants will engage in activities that assess their reaction to visual and auditory stimuli in relation to their drinking habits.

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