STEPS to Enhance Physical Activity (STEPS) after Hematopoietic Stem Cell Transplantation (HCT) for Multiple Myeloma

Studying Physical Activity for Fatigue and Quality of Life in Multiple Myeloma Patients

Recruiting
18 years - 100 years
All
Phase N/A
1 Location

Brief description of study.

The purpose of this pilot study is to test the preliminary effects of a free-living physical activity intervention, STEPS to Enhance Physical Activity (STEPS), compared to usual care on fatigue (tiredness), functional ability (ability to perform tasks associated with daily living, like moving from a sitting to standing position), muscle strength, physical activity, and quality of life in people with multiple myeloma treated with autologous hematopoietic cell transplantation (HCT).

Detailed description of study

This pilot study addresses the National Institutes of Health strategic plan to build symptom science through promotion of personalized health strategies in people with chronic and/or life-limiting illnesses. The purpose is to test the preliminary effects of a free-living physical activity intervention, STEPS to Enhance Physical Activity (STEPS), on fatigue, functional ability, muscle strength, physical activity, and quality of life in people with multiple myeloma (MM) treated with autologous hematopoietic stem cell transplantation (HCT).

Eligibility of study

You may be eligible for this study if you meet the following criteria:

  • Conditions: multiple myeloma
  • Age: 18 years - 100 years
  • Gender: All

Inclusion Criteria
Cognitively able to understand the purpose of the research
Undergoing HCT for treatment of multiple myeloma
To participate in the post-hospital phase of the intervention, subjects must be ambulatory and discharged to home.
Use of an assistive ambulation device, such as canes and walkers, is permitted.
Exclusion Criteria
Subjects who present with significant comorbidity that would make it potentially unsafe to participate in physical activity.
We will adhere to the American College of Sports Medicine guidelines and exclude those who do not meet their guidelines for exercise testing.
Evidence of restrictive lung disease or asthma, the presence of a potentially debilitating disease such as congestive heart failure, kidney disease, liver failure or cirrhosis, musculoskeletal or degenerative nerve disease, etc.
The presence of a condition that would make it potentially unsafe to participate in physical activity or functional ability tests, including a history of a recent myocardial infarction, unstable angina pectoris, uncontrolled cardiac arrhythmias causing symptoms or hemodynamic compromise, severe symptomatic aortic stenosis, uncontrolled symptomatic heart failure, and/or uncontrolled metabolic disease.
Cognitively unable to understand the purpose of the study.

Updated on 19 Feb 2024. Study ID: 1712292634 (IUSCC-0653)

This study investigates the effects of a physical activity program called STEPS to Enhance Physical Activity on people with multiple myeloma who have undergone a type of stem cell transplant. Multiple myeloma is a cancer that affects plasma cells in the bone marrow. The study aims to see how this program affects tiredness, the ability to do everyday tasks, muscle strength, physical activity levels, and overall quality of life.

Participants in the study will either follow the STEPS program or continue with their usual care. The STEPS program is designed to be a free-living intervention, meaning it can be done in the participants' everyday environments. The study will measure various outcomes like fatigue, functional ability, and muscle strength to understand the benefits of the physical activity program.

  • Who can participate: Adults undergoing hematopoietic cell transplantation for multiple myeloma who can understand the study and are able to move around at home can participate. Assistive devices like canes and walkers are allowed.
  • Study details: Participants will engage in a physical activity program or continue with usual care. The study will compare the effects of these approaches on fatigue and quality of life. Participants will be monitored for safety and effectiveness of the activities.

Find a site

Message sent successfully.
We have submitted the information you provided to the research team at the location you chose. For your records, we have sent a copy of the message to your email address.
If you would like to be informed of other studies that may be of interest to you, you may sign up for Patient Notification Service.
Sign up

Send a message

Enter your contact details to connect with study team

Investigator Avatar

Primary Contact

First name*
Last name*
Email*
Phone number*
Preferred way of contact label
Race
Ethnicity
Other language

Default Content Message Here