This study is currently not recruiting participants.

A Randomized Phase III Trial of Melphalan and Dexamethasone (MDex) Versus Bortezomib Melphalan and Dexamethasone (BMDex) for Untreated Patients with Systemic Light-Chain (AL) Amyloidosis Ineligible for Autologous Stem-Cell Transplantation

Study Comparing Standard and Investigational Combination Treatments

Not Recruiting
18 years - 100 years
All
Phase N/A

Brief description of study.

We will compare the effects, good and/or bad, of the standard two-drug combination treatment, against an experimental three-drug combination.

Detailed description of study

We will compare the effects, good and/or bad, of the standard two-drug combination treatment, against an experimental three-drug combination.

Eligibility of study

You may be eligible for this study if you meet the following criteria:

  • Conditions: Multiple Myeloma
  • Age: 18 years - 100 years
  • Gender: All

This study investigates the effects of a standard two-drug combination treatment compared to an experimental three-drug combination. The purpose is to understand how these treatments affect patients, including any potential benefits or side effects.

Participants in the study will receive either the standard two-drug treatment or the experimental three-drug treatment. The study will monitor the effects of these treatments to compare their outcomes.

  • Who can participate: Adults aged 18-65 with a diagnosis relevant to the study focus, who are not currently receiving other investigational treatments, may be eligible to participate.
  • Study details: Participants will receive either the standard two-drug combination or the investigational three-drug combination. The effects will be monitored and compared. If applicable, a placebo will be used to assess treatment efficacy, defined as a substance with no therapeutic effect used as a control in testing new drugs.
Updated on 19 Feb 2024. Study ID: 1202008117

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