This study is currently not recruiting participants.

A PHASE II STUDY OF EVEROLIMUS (RAD001) FOR CHILDREN WITH NEUROFIBROMATOSIS TYPE I AND CHEMOTHERAPY-REFRACTORY RADIOGRAPHIC PROGRESSIVE LOW-GRADE GLIOMAS

Investigating the Effects of an Investigational Medication on Low-Grade Brain Tumors in Children with Neurofibromatosis 1

Not Recruiting
1 years - 21 years
All
Phase N/A

Brief description of study.

The purpose of this research study is to learn if the study drug everolimus (RAD001) can shrink or slow the growth of low-grade gliomas in children with Neurofibromatosis 1.

Detailed description of study

The purpose of this research study is to learn if the study drug everolimus (RAD001) can shrink or slow the growth of low-grade gliomas in children with Neurofibromatosis 1.

Eligibility of study

You may be eligible for this study if you meet the following criteria:

  • Conditions: Brain Cancer
  • Age: 1 years - 21 years
  • Gender: All

This study investigates the effects of an investigational medication on low-grade gliomas in children with Neurofibromatosis 1. Neurofibromatosis 1 is a genetic disorder that often causes benign tumors on nerve tissue, which can sometimes develop into low-grade gliomas, a type of brain tumor. The purpose of this study is to see if the investigational medication can shrink or slow the growth of these tumors.

Participants will receive the investigational medication and will be monitored for changes in tumor size and growth. The study involves regular medical assessments to evaluate the effects of the treatment on the gliomas.

  • Who can participate: Children aged 5-18 years diagnosed with Neurofibromatosis 1 and low-grade gliomas are eligible to participate.
  • Study details: Participants will take the investigational medication and undergo regular assessments to monitor tumor response. A placebo is not used in this study.
Updated on 19 Feb 2024. Study ID: 1209009648

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