Effects of Stannous Fluoride on Porphyromonas gingivalis Stimulated and Unstimulated Human Gingival Fibroblasts: Toxicity Matrix Metalloproteinase Expression and COLIA Expression
Study on Fluoride Effects on Gum Cells
Brief description of study.
We will test the effects of stannous fluoride and sodium fluoride on human gingival fibroblasts in terms of expression of matrix metalloprotienases and type I collagen in an in vitro environment.
Detailed description of study
We will test the effects of stannous fluoride and sodium fluoride on human gingival fibroblasts in terms of expression of matrix metalloprotienases and type I collagen in an in vitro environment.
Eligibility of study
You may be eligible for this study if you meet the following criteria:
- Conditions: Human Gingival Fibroblasts
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Age: 100 years or below
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Gender: All
This study investigates the effects of different types of fluoride on gum cells. Specifically, it looks at how stannous fluoride and sodium fluoride affect the production of certain proteins in the cells that make up the gums. These proteins include matrix metalloproteinases, which help break down proteins, and type I collagen, which provides structure and strength to tissues.
Participants in the study will have their gum cells exposed to these fluoride types in a controlled laboratory setting. The study will measure changes in the levels of these proteins to understand how the different fluoride types impact gum health.
- Who can participate: This is an in vitro study and does not involve human participants.
- Study details: The study involves testing human gingival fibroblasts with fluoride in a lab to compare effects on protein levels.
Interested in the study?
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