Dopamine prediction error and human alcohol consumption

Investigation of Dopamine Release Detection Using Positron Emission Tomography (PET) Imaging

Recruiting
21 years - 55 years
All
Phase N/A
1 Location

Brief description of study.

The purpose of this study is to find out if PET can detect the release of dopamine from nerve endings into synapses, and how the amount of dopamine released varies with the consumption of alcohol or caffeine.

Detailed description of study

This study takes about 10 hours over 2-3 days.  Up to $200 for participation.  We are interested in people who regularly use alcohol and people who drink alcohol occasionally.  If you qualify, you'll get an MRI scan and PET scans of your brain.
Participants will be paid for their participation.
Participants will be paid for their participation.

Eligibility of study

You may be eligible for this study if you meet the following criteria:

  • Conditions: Effects of Alcohol Consumption,Healthy,Alcohol,Dopamine
  • Age: 21 years - 55 years
  • Gender: All

Inclusion Criteria                                                                               
Drink alcohol either regularly or occasionally

This study investigates how PET imaging can detect dopamine release in the brain. Dopamine is a chemical in the brain that helps transmit signals between nerve cells. The study looks at how dopamine release changes when people consume alcohol or caffeine.

Participants will undergo MRI and PET scans to monitor brain activity. MRI stands for Magnetic Resonance Imaging, which creates detailed images of the organs and tissues. PET stands for Positron Emission Tomography, which shows how tissues and organs are functioning.

  • Who can participate: Adults who drink alcohol regularly or occasionally are eligible to participate.
  • Study details: Participants will have MRI and PET scans of their brain. A PET scan involves a small amount of radioactive material to show activity in the body.
Updated on 19 Feb 2024. Study ID: 1011003783

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