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Found 410 ctsi-central-admin trials

A listing of ctsi-central-admin medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Research on Inflammatory Breast Cancer Specimens

18 years - 100 years
All genders
This study investigates inflammatory breast cancer by collecting specimens from patients. Inflammatory breast cancer is a rare and aggressive form of breast cancer that causes redness and swelling in the breast. Researchers aim to understand how this disease develops and progresses by examining the collected specimens.Participants will provide clinical information …
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Study on Investigational Approaches for Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia

2 years - 21 years
All genders
This study investigates treatments for Philadelphia chromosome positive acute lymphoblastic leukemia (ALL), a type of cancer affecting the blood and bone marrow. The purpose of this study is to examine the effectiveness of combining an investigational medication with different chemotherapy approaches to improve disease-free survival in children with standard risk …
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How Adults Process Sensory Information

18 years - 100 years
All genders
This study investigates how young and older adults process sensory information from vision and proprioception, which is the sense of body position. The purpose is to understand if older adults combine these senses in a way that reduces errors and how they adjust to changes in spatial alignment compared to …
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Investigation of Genetic Testing-Directed Treatment for Pediatric Tumors

1 years - 21 years
All genders
This study investigates how well treatment directed by genetic testing works in children with certain cancers like solid tumors, non-Hodgkin lymphomas, or histiocytic disorders. These are conditions where cells grow uncontrollably in different parts of the body. The study aims to find out if specific changes in genes can be …
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Study on Investigational Medication and Chemotherapy in Infants with a Type of Blood Cancer

1 years or below
All genders
This study investigates the effects of an investigational medication combined with chemotherapy in infants who have a specific type of leukemia called acute lymphoblastic leukemia (ALL) with a KMT2A gene rearrangement. The purpose of the study is to see if the investigational medication can be safely added to the standard …
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Study on Investigational Medication Combination for Pediatric Tumors

2 years - 21 years
All genders
This study investigates the effects of a combination of investigational medications on pediatric subjects with certain types of recurrent or refractory solid tumors. The purpose is to find the highest safe dose of these medications when given together, and to understand how the body processes them. Additionally, researchers will study …
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Investigation of Safety of an Investigational Medication Alone or with an Antibody

18 years - 100 years
All genders
The purpose of this study is to investigate the safety of an investigational medication when given alone or with an antibody that targets a protein called PD-L1. PD-L1 is involved in the body's immune response, and targeting it can help enhance the body's ability to fight cancer. This study focuses …
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Investigating Exposure to Semi-Volatile Chemicals in Children

6 years - 10 years
All genders
The purpose of this study is to investigate personal exposure to a group of semi-volatile chemicals in children of Alaska Native communities. Semi-volatile chemicals are substances that can easily become gases at room temperature. This study focuses on semi-volatile organic compounds, specifically flame retardants and polycyclic aromatic hydrocarbons, which are …
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Investigation of Treatments for Metastatic Castration-Resistant Prostate Cancer with DNA Repair Defects

18 years - 100 years
Male
This study investigates treatments for men with metastatic castration-resistant prostate cancer (mCRPC) who have DNA repair defects. The purpose is to assess the effectiveness of two drugs that are approved by the US FDA, both individually and in combination. Metastatic castration-resistant prostate cancer is a type of prostate cancer that …
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Study on Reduced Radiation and Chemotherapy for WNT-driven (a type of genetic alteration associated with medulloblastoma) Medulloblastoma

3 years - 21 years
All genders
This study investigates how well reduced doses of radiation therapy and chemotherapy work in treating patients with a type of brain tumor called WNT-driven medulloblastoma. Medulloblastoma is a cancerous brain tumor that starts in the lower back part of the brain and can spread to other areas. The study aims …
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