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Found 416 ctsi-central-admin trials

A listing of ctsi-central-admin medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Study on Investigational Medication Combination for Pediatric Tumors

2 - 21
All genders
This study investigates the effects of a combination of investigational medications on pediatric subjects with certain types of recurrent or refractory solid tumors. The purpose is to find the highest safe dose of these medications when given together, and to understand how the body processes them. Additionally, researchers will study …
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Investigation of Safety of an Investigational Medication Alone or with an Antibody

18 - 100
All genders
The purpose of this study is to investigate the safety of an investigational medication when given alone or with an antibody that targets a protein called PD-L1. PD-L1 is involved in the body's immune response, and targeting it can help enhance the body's ability to fight cancer. This study focuses …
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Investigating Exposure to Semi-Volatile Chemicals in Children

6 - 10
All genders
The purpose of this study is to investigate personal exposure to a group of semi-volatile chemicals in children of Alaska Native communities. Semi-volatile chemicals are substances that can easily become gases at room temperature. This study focuses on semi-volatile organic compounds, specifically flame retardants and polycyclic aromatic hydrocarbons, which are …
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Investigation of Treatments for Metastatic Castration-Resistant Prostate Cancer with DNA Repair Defects

18 - 100
Male
This study investigates treatments for men with metastatic castration-resistant prostate cancer (mCRPC) who have DNA repair defects. The purpose is to assess the effectiveness of two drugs that are approved by the US FDA, both individually and in combination. Metastatic castration-resistant prostate cancer is a type of prostate cancer that …
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Study on Reduced Radiation and Chemotherapy for WNT-driven (a type of genetic alteration associated with medulloblastoma) Medulloblastoma

3 - 21
All genders
This study investigates how well reduced doses of radiation therapy and chemotherapy work in treating patients with a type of brain tumor called WNT-driven medulloblastoma. Medulloblastoma is a cancerous brain tumor that starts in the lower back part of the brain and can spread to other areas. The study aims …
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Study on Speaker Information and Speech Perception

18 - 35
All genders
This study investigates how the expectations of speech, influenced by information about the speaker, affect how people perceive speech. It aims to understand the relationship between what we know about a speaker and how we interpret their words. Speech perception is how our brain processes and understands spoken language.Participants in …
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Study on Body Composition and Investigational Treatment Side Effects in Pancreatic Cancer

18 - 100
All genders
This study investigates the relationship between body composition, which includes muscle and fat mass, and the side effects experienced by patients undergoing a common chemotherapy treatment. This treatment is used for individuals with advanced, metastatic, or recurrent pancreatic cancer, a condition where cancer cells form in the tissues of the …
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Investigating Treatment Effects of an Investigational Antibody in High-Risk Neuroblastoma

1 - 100
All genders
This study investigates the treatment effects of an investigational antibody in children and adults with high-risk neuroblastoma. Neuroblastoma is a type of cancer that forms in certain types of nerve tissue, and high-risk means that the cancer is more likely to come back or spread. The study focuses on patients …
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Investigating the Effects of an Investigational Medication with Chemotherapy for Advanced Cancer of the Uterus Lining

18 - 100
Female
This study investigates the effects of an investigational medication combined with chemotherapy for women with advanced or recurrent endometrial cancer. Endometrial cancer affects the lining of the uterus, and this study aims to understand how the investigational medication, when used with standard chemotherapy drugs, impacts the condition.Participants in the study …
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Study on Breast Cancer Screening Methods

45 - 74
Female
This study investigates the effectiveness of two methods for breast cancer screening: digital tomosynthesis mammography and digital mammography. The purpose of this study is to compare how often advanced breast cancer occurs in participants who are screened using these two methods over a period of 4.5 years. Digital tomosynthesis mammography …
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