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Found 410 ctsi-central-admin trials

A listing of ctsi-central-admin medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Investigating Treatment Options for Mantle Cell Lymphoma (MCL) in First Complete Remission

100 years or below
All genders
This study investigates treatment options for patients with mantle cell lymphoma (MCL) who are in their first complete remission and are negative for minimal residual disease (MRD). The study compares two approaches: one group of patients will receive an autologous hematopoietic cell transplant (auto-HCT) followed by maintenance therapy, and the …
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Investigating Treatment Effects of an Investigational Antibody in Pediatric Neuroblastoma

18 years or below
All genders
This study investigates the effects of an investigational antibody treatment for children with a type of cancer called neuroblastoma that has spread to the brain or the lining of the brain and spinal cord. Neuroblastoma is a cancer that starts in young nerve cells and can spread to other parts …
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Colorectal Cancer: Blood Tests for Recurrence Detection

18 years - 100 years
All genders
This study investigates the use of blood tests to detect the return of colorectal cancer. Colorectal cancer, or CRC, is a type of cancer that affects the colon or rectum. The study compares two tests: Colvera, which looks for specific DNA changes in the blood, and the CEA test, which …
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Investigating an Investigational Medication for Pediatric Sarcomas

1 years - 18 years
All genders
This study investigates the use of an investigational medication in children and adolescents with certain types of cancers that have come back or have not responded to treatment. These cancers include rhabdomyosarcoma (RMS), non-rhabdomyosarcoma soft tissue sarcoma (NRSTS), and Ewing sarcoma (EWS). The purpose is to assess the safety and …
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Investigation of Web-Based Physical Activity for Children with Acute Lymphoblastic Leukemia

8 years - 15 years
All genders
This study investigates how a web-based physical activity program can improve long-term health in children and adolescents with acute lymphoblastic leukemia (ALL). ALL is a type of cancer that affects the blood and bone marrow. The study focuses on participants who have shown a reduction or disappearance of symptoms after …
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Investigating Treatment for Stage IV Non-Squamous NSCLC

18 years - 100 years
All genders
This study investigates the combination of several treatments for patients with stage IV non-squamous non-small cell lung cancer (NSCLC). The purpose is to understand how well these treatments work together to stop the cancer from growing or spreading. NSCLC is a type of lung cancer that does not include squamous …
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Investigating the Effects of an Investigational Medication with Chemotherapy for Urinary Tract Cancer

18 years - 100 years
All genders
This study investigates the effects of using an investigational medication along with usual chemotherapy for patients with urothelial carcinoma, which is a type of cancer that affects the urinary tract. The purpose is to see if this combination can improve progression-free survival (PFS) in patients who cannot use cisplatin, a …
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Investigating Social Functioning in Individuals with Schizophrenia and Healthy Controls

18 years - 60 years
Accepts healthy volunteer
All genders
This study investigates social functioning in everyday life for people with schizophrenia compared to healthy controls, who are individuals without schizophrenia. Schizophrenia is a mental health condition that affects how a person thinks, feels, and behaves, often leading to difficulties in distinguishing between what is real and imaginary.Participants will undergo …
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Study on Immune Modulation in Pancreatic Cancer Involving RIPK1 Protein

18 years - 100 years
All genders
This study investigates how inhibiting a protein called RIPK1 might affect the immune system in patients with pancreatic cancer. RIPK1 is a gene that has been linked to resistance against immunotherapy, a type of cancer treatment that helps the immune system fight cancer. In animal studies, blocking RIPK1 in pancreatic …
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Investigational Treatment Access for Blood Cancer Patients

100 years or below
All genders
This study investigates the use of an investigational treatment for patients with certain types of blood cancer, specifically acute lymphoblastic leukemia (ALL) and diffuse large B-cell lymphoma (DLBCL). These patients have a special need due to their leukapheresis product not meeting standard specifications. Leukapheresis is a procedure to collect blood …
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