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Found 199 Neoplasm trials

A listing of Neoplasm medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Investigation of an Investigational Vaccine and Treatment for HPV-related Head and Neck Cancer

18 years - 100 years
All genders
This study investigates the use of an investigational vaccine combined with an immune therapy to treat patients with head and neck cancer linked to the human papilloma virus (HPV). Head and neck cancer can occur in areas such as the throat, mouth, and nose, and when linked to HPV, it …
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Investigation of Surgery for Treating Testicular Seminoma

16 years - 100 years
All genders
The purpose of this study is to evaluate the safety and effectiveness of Retroperitoneal Lymph Node Dissection (RPLND) as a treatment for seminoma that has spread to the lymph nodes in the retroperitoneum. The retroperitoneum is an area in the body located behind the intestines and is often the first …
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Study on Blood and Tissue Sample Collection for Thymus-related Conditions

18 years - 100 years
All genders
This study investigates the collection of blood and tissue samples from patients with thymoma or thymic carcinoma. Thymoma and thymic carcinoma are types of cancer that originate from the thymus, a small organ located in the upper chest. The purpose of collecting these samples is for laboratory evaluation to better …
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Investigating Bone Destruction Markers in Myeloma: A Cancer Affecting Plasma Cells

18 years - 95 years
All genders
This study investigates if certain substances that might cause bone destruction are found in higher levels in the blood or bone marrow of people with myeloma. Myeloma is a type of cancer that affects plasma cells in the bone marrow. The study will compare these levels in patients with newly …
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Investigating Combination Chemotherapy for Ewing Sarcoma Spread to Other Parts of the Body

50 years or below
All genders
This study investigates the effectiveness of combination chemotherapy with or without an investigational medication in treating patients with Ewing sarcoma that has spread to other parts of the body. Ewing sarcoma is a type of cancer that forms in bone or soft tissue. The purpose of this study is to …
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Study on Investigational Medications for Glioma with BRAF V600 Mutation

1 years - 17 years
All genders
This study investigates the use of investigational medications in children and adolescents with a specific type of brain tumor called glioma. Glioma is a type of tumor that occurs in the brain and spinal cord. The study focuses on patients who have a BRAF V600 mutation, which is a change …
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Studying Physical Activity for Fatigue and Quality of Life in Multiple Myeloma Patients

18 years - 100 years
All genders
This study investigates the effects of a physical activity program called STEPS to Enhance Physical Activity on people with multiple myeloma who have undergone a type of stem cell transplant. Multiple myeloma is a cancer that affects plasma cells in the bone marrow. The study aims to see how this …
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Investigating the Effect of an Investigational Medication with R-CHOP on Survival in High-Risk Diffuse Large B-Cell Lymphoma

18 years - 100 years
All genders
This study investigates the effects of an investigational medication combined with R-CHOP treatment on overall survival in patients with high-risk Diffuse Large B-Cell Lymphoma (DLBCL) who have a specific biomarker called DGM1. DLBCL is a type of cancer that affects white blood cells. The study aims to see if adding …
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Investigating Treatments for Anaplastic Large Cell Lymphoma (ALCL)

21 years or below
All genders
This study investigates how well different treatments work for patients with a type of cancer called anaplastic large cell lymphoma (ALCL). ALCL is a cancer that affects the lymph nodes and is characterized by certain markers on the cancer cells, like CD30 and ALK. The study is testing two treatment …
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Study on Radiation and Chemotherapy Treatments for Head and Neck Cancer

18 years - 100 years
All genders
Phase 2
Interventional
This study investigates treatment options for patients with head and neck cancer. The purpose is to compare two different approaches used after surgery. One approach involves using radiation therapy by itself, while the other combines radiation therapy with an investigational chemotherapy medication. Head and neck cancer refers to cancers that …
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