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Found 189 Neoplasm trials

A listing of Neoplasm medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Investigation of an Investigational Treatment for Diabetes

100 years or below
Female
Who can participate: Adults aged 18-65 with a diagnosis of type 2 diabetes, who are currently on stable medication regimens, may be eligible to participate. Exclusion criteria include individuals with type 1 diabetes or those with a history of severe hypoglycemia.Study details: Participants will be randomly assigned to receive either …
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Investigating Cognitive Changes After Chemotherapy

19 years - 55 years
Female
The purpose of this study is to understand how chemotherapy affects brain function and brain chemistry. The study is looking at cognitive deficits, which means changes in memory and thinking skills, in breast cancer survivors compared to healthy women. This study investigates how these changes occur after chemotherapy treatment.Participants will …
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Investigating the Effects of Radium-223 (a radioactive substance targeting bone metastases) with Chemotherapy in Prostate Cancer

19 months - 204 months
Male
This study investigates the effects of combining radium-223 with a chemotherapy treatment called docetaxel in patients with prostate cancer that has spread to the bones. The study aims to compare the outcomes of this combination treatment with those of using docetaxel alone. Prostate cancer is a condition where cancer cells …
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Optimizing Subcutaneous FEntanyl titRation: RApid Achievement of Adequate Exposure When Treating Cancer-Related paIn. (FERRARI)

S
Suresh Kumar
18 years - 120 years
All genders
Phase 4
Interventional
The primary objective is to evaluate the effect of loading boluses when dose incresaing treatment with SC fentanyl in patients with cancer. The primary endpoint of this study is to prove the non-inferiority of fentanyl plasma concentrations 12 hours after dose augmentation compared to 48 hours after dose augmentation within …
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Study on Investigational Medication with Chemotherapy for Ovarian Cancer

18 years - 100 years
Female
This study investigates the effects of an investigational medication combined with a standard chemotherapy drug called paclitaxel in patients with ovarian cancer. Ovarian cancer is a disease where cancer cells form in the tissues of the ovary. The study aims to compare the investigational medication and paclitaxel with a combination …
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Investigating Investigational Antibiotics for Preventing Infections After Surgery

18 years - 100 years
All genders
This study investigates the effectiveness of two antibiotics, cefoxitin and piperacillin-tazobactam, in preventing infections at the site of surgery after a procedure called pancreatoduodenectomy. A pancreatoduodenectomy is a surgery to remove part of the pancreas and nearby organs. The study uses data from the American College of Surgeons National Surgical …
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Investigation of Safety of an Investigational Medication Alone or with an Antibody

18 years - 100 years
All genders
The purpose of this study is to investigate the safety of an investigational medication when given alone or with an antibody that targets a protein called PD-L1. PD-L1 is involved in the body's immune response, and targeting it can help enhance the body's ability to fight cancer. This study focuses …
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Investigating Treatment for CD22+ B-ALL in Children

1 years - 21 years
All genders
This study investigates the effectiveness of an investigational medication in treating children with a type of blood cancer called CD22 positive B acute lymphoblastic leukemia (B-ALL) that has either come back after treatment or does not respond to treatment. B-ALL is a cancer of the white blood cells, and CD22 …
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Investigating Non-TBI Conditioning for B-cell Acute Lymphoblastic Leukemia Patients Undergoing Hematopoietic Cell Transplant

1 years - 25 years
All genders
This study investigates the use of non-total body irradiation (non-TBI) conditioning for patients with B-cell Acute Lymphoblastic Leukemia (B-ALL) who are at low risk of relapse. B-ALL is a type of cancer that affects the blood and bone marrow. The study focuses on patients who do not have minimal residual …
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