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Found 204 Neoplasms trials

A listing of Neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Study on Immune Modulation in Pancreatic Cancer Involving RIPK1 Protein

18 - 100
All genders
This study investigates how inhibiting a protein called RIPK1 might affect the immune system in patients with pancreatic cancer. RIPK1 is a gene that has been linked to resistance against immunotherapy, a type of cancer treatment that helps the immune system fight cancer. In animal studies, blocking RIPK1 in pancreatic …
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Research Study on Observation vs. Radiation Therapy After Surgery for Grade II Meningioma

18 - 100
All genders
Phase 3
Interventional
This study investigates the effects of two different approaches after surgery for grade II meningioma, a type of brain tumor. The purpose of this study is to compare the outcomes of observation alone versus radiation therapy following surgery. Participants will be randomly assigned to either continue with observation or receive …
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Investigating Methods to Increase Cancer Screening Rates in Rural Women

50 - 74
Female
This study investigates different methods to increase screening rates for Breast Cancer, Cervical Cancer, and Colorectal Cancer among women aged 50 to 74 living in rural areas. The study compares the use of a tailored interactive DVD (TIDVD), a combination of telephone patient navigation and TIDVD, and usual care to …
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Study of Investigational Medication for Children with Cancer

1 - 17
All genders
This study investigates an investigational medication to understand its safety, tolerability, and effects on tumors in children with cancer. The purpose is to determine the highest dose that can be given safely without causing serious side effects. The study will also examine how the medication is absorbed and broken down …
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Investigating the Effects of an Investigational Medication with or without an Additional Agent in Treating Solid Tumors That Have Returned or Are Resistant to Treatment in Younger Patients

1 - 30
All genders
This study investigates the effects of an investigational medication, given with or without an additional agent, on younger patients with solid tumors or sarcomas that have either returned after treatment or do not respond to treatment. Solid tumors are masses of tissue that can occur in various parts of the …
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Study on the Safety of an Investigational Medication for Blood Cancers

18 - 100
All genders
This study investigates the effectiveness, safety, and tolerability of an investigational medication for patients with relapsed or refractory blood cancers, which are also known as hematologic malignancies. These are cancers that affect the blood, bone marrow, and lymph nodes. The study aims to understand how well the medication works and …
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Study on the Effectiveness of Investigational Medication After Surgery and Chemotherapy for Lung Cancer (Non-Small Cell)

18 - 100
All genders
This study investigates how well an investigational medication works after surgery and chemotherapy in treating patients with stage IB-IIIA non-small cell lung cancer. Non-small cell lung cancer is a type of lung cancer that includes several subtypes, and it is categorized based on tumor size and spread. The study aims …
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Investigation of Investigational Medication in Treating Rare Tumors in Young Patients

2 - 30
All genders
This study investigates how well an investigational medication works in treating young patients with sarcomas, Wilms tumor, or other rare tumors. These tumors may have returned, not responded to therapy, or been newly diagnosed. The purpose is to determine the rate at which these tumors respond to the investigational medication.Participants …
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Study on Combination Chemotherapy with Investigational Medication for Stage III Colon Cancer

18 - 100
All genders
This study investigates the effectiveness of combination chemotherapy with an investigational medication compared to chemotherapy alone in patients with stage III colon cancer. The focus is on patients with a specific condition called deficient DNA mismatch repair (dMMR), which is when the body's natural ability to fix DNA mistakes is …
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Investigating Total Marrow Irradiation for Stem Cell Transplant Preparation

18 - 65
All genders
This study investigates a new type of radiation therapy called total marrow irradiation (TMI) for patients undergoing allogeneic hematopoietic stem cell transplantation (Allo-HSCT). It aims to find the most effective dose of TMI when used with a chemotherapy drug called fludarabine. This combination is used to prepare patients for the …
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