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Found 410 ctsi-central-admin trials

A listing of ctsi-central-admin medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Investigating Priming Before Chemotherapy in Children with AML

22 years or below
All genders
This study investigates the safety and effectiveness of using DNA methyltransferase inhibitors (DMTi) before chemotherapy in treating children with acute myeloid leukemia (AML). DNA methyltransferase inhibitors are substances that may help in modifying the genes' activity without changing the DNA sequence itself. The purpose is to see if these inhibitors …
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Investigating the Safety and Effects of an Investigational Vaccine on Breast Cancer Recurrence

18 years - 100 years
All genders
This study investigates the safety of an investigational vaccine in patients with HER2 positive breast cancer. HER2 positive breast cancer is a type of breast cancer that tests positive for a protein called human epidermal growth factor receptor 2, which promotes the growth of cancer cells. The study also looks …
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Study on Reducing Acute Myeloid Leukemia (AML) Recurrence with Additional Treatment

60 years - 100 years
All genders
This study investigates whether adding an investigational medication to the usual treatment can lower the chances of acute myeloid leukemia (AML) returning or worsening. AML is a type of cancer that affects the blood and bone marrow, where blood cells are made. The study aims to find out if the …
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Comparing Graft-versus-Host Disease (GVHD) Prophylaxis Regimens for Survival Outcomes

18 years - 100 years
All genders
This study investigates two different methods for preventing graft-versus-host disease (GVHD) in patients who have undergone a transplant. GVHD is a condition where the transplanted cells attack the recipient's body. The study aims to see which method better supports survival without GVHD or cancer relapse over one year.Participants will undergo …
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Study on Understanding Speech in Aphasia

18 years - 35 years
Accepts healthy volunteer
All genders
This study investigates how well people can understand the speech of individuals with aphasia compared to those without the condition. Aphasia affects a person's ability to communicate, leading to fluent but nonsensical speech or non-fluent speech that is hard to comprehend. The study aims to explore these differences in speech …
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Investigating Investigational Agricultural Practices and Professional Development

18 years - 100 years
All genders
This study investigates innovative agricultural practices carried out by experimental farms in the United States and Asia. These farms are unique because they are run by individuals who have transitioned from non-agricultural professions. They view farming as a research activity and focus on working with disadvantaged individuals to support their …
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Study on Repetitive Transcranial Magnetic Stimulation (rTMS) for Schizophrenia

18 years - 45 years
All genders
Interventional
This study investigates the use of repetitive transcranial magnetic stimulation (rTMS) for individuals with schizophrenia or schizoaffective disorder. Schizophrenia is a mental health condition that affects how a person thinks, feels, and behaves. The purpose of this study is to see if rTMS can improve symptoms and communication between brain …
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Investigating Hearing Protection Education via Smartphone Apps for Adolescent Farmworkers

13 years - 18 years
All genders
This study investigates how hearing conservation education delivered through smartphone apps can affect the use of hearing protection among adolescent farmworkers in rural Indiana. The study focuses on adolescents aged 13 to 17 who live or work on farms and attend school regularly. Hearing conservation refers to practices and strategies …
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Investigating Sleep Monitoring Technologies for Cognitive Impairment

18 years - 100 years
Accepts healthy volunteer
All genders
This study investigates sleep disturbances in people with Alzheimer's Disease, mild cognitive impairment, and their caregivers. Sleep disturbances can include problems like insomnia or irregular sleep patterns. The study will use a new no-contact sleep sensor, called the Sleep Monitor, to track sleep patterns. It will compare the Sleep Monitor's …
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Investigational Medication for Acute Myeloid Leukemia

18 years - 100 years
All genders
Phase 1/2
This study investigates the safety and effectiveness of combining two investigational medications for treating acute myeloid leukemia (AML). AML is a type of cancer that affects the blood and bone marrow. The study will look at how many patients respond to treatment with these investigational medications.Participants will receive the investigational …
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