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Found 410 ctsi-central-admin trials

A listing of ctsi-central-admin medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

School Evaluation and Supports of Children with Pelizaeus-Merzbacher disease

3 - 25
All genders
Describe how schools look at the needs of children with Pelizaeus-Merzbacher disease and how schools support those children in their school environment to help with learning needs
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A RANDOMIZED, PHASE II STUDY COMPARING TRASTUZUMAB AND VINORELBINE IN COMBINATION WITH AVELUMAB OR AVELUMAB AND UTOMILUMAB (41BB/CD137 AGONIST), IN PATIENTS WITH HER2-POSITIVE METASTATIC BREAST CANCER WHO HAVE PROGRESSED ON PRIOR TRASTUZUMAB AND PERTUZUMAB: The "AVIATOR" Study

18 - 100
All genders
Phase 2
To determine whether the addition of avelumab to the combination of trastuzumab and vinorelbine will improve progression-free survival (PFS) compared to the trastuzumab and vinorelbine combination alone in patients with advanced HER2-positive breast cancer. To determine whether the addition of utomilumab to the combination of avelumab, trastuzumab, and vinorelbine will …
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Repetitive Transcranial Magnetic Stimulation as a Probe of Episodic Memory Neurocircuitry in Schizophrenia

18 - 40
All genders
This study proposes to combine functional magnetic resonance imaging (fMRI) with inhibitory Low Frequency (1 Hz) and excitatory High Frequency (20 Hz) repetitive Transcranial Magnetic Stimulationn (rTMS) in schizophrenia.
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Neural correlates of consumers' mental imagery.

18 - 55
Accepts healthy volunteer
Female
The purpose of this study is to investigate how the brain processes various stimuli in the context of consumer decision-making. This study will identify the neural correlates of consumers' mental imagery.
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The effect of foot type on ankle movement during an inversion perturbation

18 - 26
Accepts healthy volunteer
All genders
The proposed study aims to determine if different foot types have an impact on maximum inversion, time to maximum inversion, and inversion velocity during a dynamic perturbation task.
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Insights into the Lid Margin: Characterization of Membrane Associated Mucins in Ocular Surface Disease

18 - 100
Accepts healthy volunteer
All genders
Dry eye disease affects millions of people worldwide and due to an incomplete understanding of the pathogenesis of the disease, it is widely underdiagnosed and undermanaged by clinicians. Understanding the contribution of the proteins involved in maintaining boundary lubrication between the ocular surface and eyelids, specifically mucins, may lead to …
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Effects of Kinesio tape on Delayed Onset Muscle Soreness

18 - 30
Accepts healthy volunteer
All genders
The purpose of this study is to determine the effect of Kinesio tape on delayed onset muscle soreness of the biceps muscle of your arm following strenuous eccentric exercise of the bicep muscle. Delayed onset muscle soreness is the pain and stiffness felt in the muscles several hours to days …
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Profiling Between-limb Differences for Prospectively Injured and Uninjured Runners: A Dynamical Measures Approach

18 - 45
Accepts healthy volunteer
All genders
The purpose of this study is: 1) to determine natural and healthy levels of movement pattern differences between the right and left limb 2) to determine whether these differences may be related to the risk of developing a running related injury.
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Gait Monitoring Study.

18 - 100
Accepts healthy volunteer
All genders
The purpose of the study is to learn about the gait characteristics of persons with Alzheimer’s disease and related dementias (ADRD). We also want to understand how we should design and implement a tool to monitor gait. To this end, the "Gait Monitoring Study" (a.k.a., AlzInsole) gathers requirements by interviewing …
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EFFECTS OF ALCOHOLIC HEPATITIS ON IMMUNOLOGICAL AND VIROLOGICAL PROFILES IN HIV-POSITIVE PATIENTS.

21 - 100
All genders
The primary objective of this study is to determine the relationships between alcohol consumption and HIV-related pathogenic processes (microbial translocation, immune activation, inflammation, HIV replication, and hepatitis). Two study groups will be assembled and followed longitudinally to address this objective. Group 1 will include HIV-positive, ART-treated, heavy alcohol drinkers who …
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