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Found 412 ctsi-central-admin trials

A listing of ctsi-central-admin medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Investigation of an Investigational Vaccine and Treatment for HPV-related Head and Neck Cancer

18 years - 100 years
All genders
This study investigates the use of an investigational vaccine combined with an immune therapy to treat patients with head and neck cancer linked to the human papilloma virus (HPV). Head and neck cancer can occur in areas such as the throat, mouth, and nose, and when linked to HPV, it …
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Investigational Medication for Acute Myeloid Leukemia with FLT3 Mutation

18 years - 60 years
All genders
This study investigates the treatment of acute myeloid leukemia (AML) in patients with a specific genetic change called FLT3 mutation. The purpose is to compare two investigational medications given after initial and follow-up chemotherapy, as well as after bone marrow transplant, to see which is more effective in extending the …
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Investigation of Medications for Treating Low Blood Sugar (Hypoglycemia) Levels

6 years - 17 years
All genders
This study investigates the effectiveness of different medications in treating low blood sugar, also known as hypoglycemia. Hypoglycemia is a condition where blood sugar levels drop too low, which can be dangerous if not treated. The study aims to find the best treatment options for managing this condition in patients …
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Study to Develop a Test for Identifying Causes of Diabetes

40 years - 85 years
All genders
This study investigates the causes of diabetes related to the pancreas, such as chronic pancreatitis or pancreatic cancer, compared to type 2 diabetes. Diabetes mellitus is a condition characterized by high blood sugar levels. This study aims to develop a test to distinguish between diabetes caused by pancreatic issues and …
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Investigation of Web-Based Physical Activity for Children with Acute Lymphoblastic Leukemia

8 years - 15 years
All genders
This study investigates how a web-based physical activity program can improve long-term health in children and adolescents with acute lymphoblastic leukemia (ALL). ALL is a type of cancer that affects the blood and bone marrow. The study focuses on participants who have shown a reduction or disappearance of symptoms after …
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Study on Immune Modulation in Pancreatic Cancer Involving RIPK1 Protein

18 years - 100 years
All genders
This study investigates how inhibiting a protein called RIPK1 might affect the immune system in patients with pancreatic cancer. RIPK1 is a gene that has been linked to resistance against immunotherapy, a type of cancer treatment that helps the immune system fight cancer. In animal studies, blocking RIPK1 in pancreatic …
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Study on Investigational Medication Combination with Chemotherapy for Small Cell Lung Cancer

18 years - 100 years
All genders
This study investigates the effectiveness of combining an investigational medication with carboplatin for treating small cell lung cancer. Small cell lung cancer is a type of cancer that usually starts in the breathing tubes and spreads quickly. The study aims to compare this combination to the usual treatment methods to …
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Investigating Survival in Patients Based on Donor Match Likelihood

100 years or below
All genders
This study investigates the survival outcomes of patients with certain blood disorders who are likely or unlikely to find a matched unrelated donor (MUD) for a transplant. The conditions include acute myeloid leukemia (AML), acute lymphoblastic leukemia (ALL), myelodysplastic syndromes (MDS), non-Hodgkin lymphoma (NHL), Hodgkin lymphoma (HL), aplastic anemia (AA), …
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Investigating Priming Before Chemotherapy in Children with AML

22 years or below
All genders
This study investigates the safety and effectiveness of using DNA methyltransferase inhibitors (DMTi) before chemotherapy in treating children with acute myeloid leukemia (AML). DNA methyltransferase inhibitors are substances that may help in modifying the genes' activity without changing the DNA sequence itself. The purpose is to see if these inhibitors …
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Investigating Treatment Combinations for Advanced Lung Cancer

18 years - 100 years
All genders
Phase 2
This study investigates the effectiveness of combining an investigational medication with another treatment for patients with advanced non-small cell lung cancer (NSCLC) that has a specific gene mutation called epidermal growth factor receptor (EGFR). NSCLC is a type of lung cancer, and EGFR mutations can affect how cancer grows. The …
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