Found 412 ctsi-central-admin trials
A listing of ctsi-central-admin medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
This study investigates the effects of whole brain radiation therapy (WBRT) combined with a higher dose of radiation targeted at individual brain tumors. Researchers want to understand how this treatment impacts tumor control, memory, and specific thought processes. WBRT is a treatment that uses radiation to target the entire brain, …
This study investigates the safety and best dose of an investigational medication given with chemotherapy drugs, temozolomide and irinotecan, in children with solid tumors that have returned or not responded to treatment. Solid tumors are growths of abnormal cells that can occur in various parts of the body. This study …
This study investigates the effects of a combination of investigational medications on pediatric subjects with certain types of recurrent or refractory solid tumors. The purpose is to find the highest safe dose of these medications when given together, and to understand how the body processes them. Additionally, researchers will study …
This study investigates the use of pre-operative stereotactic radiosurgery followed by surgery in patients with brain metastases. Brain metastases occur when cancer cells spread to the brain from another part of the body. The goal is to evaluate how well this treatment approach controls the cancer in the brain six …
This study investigates the effects of an investigational antibody in treating children with solid tumors that have come back or do not respond to treatment. The purpose of this study is to find the best dose and understand the side effects of the investigational antibody. The study focuses on children …
This study investigates the effects of an investigational medication combined with R-CHOP treatment on overall survival in patients with high-risk Diffuse Large B-Cell Lymphoma (DLBCL) who have a specific biomarker called DGM1. DLBCL is a type of cancer that affects white blood cells. The study aims to see if adding …
This study investigates the effects of an investigational medication in patients with triple-negative breast cancer (TNBC). Triple-negative breast cancer is a type of cancer that does not have estrogen receptors, progesterone receptors, or HER2 protein, which are common targets in other breast cancer treatments. The purpose of this study is …
This study investigates the effects of an investigational medication for treating advanced solid tumors with a specific KRAS mutation. These are tumors that have a change in the KRAS gene, which can cause cancer cells to grow. The study is in Phase 1, which means it is the first time …
This study investigates how educational pamphlets are used by caregivers of women with dementia. It aims to understand how these caregivers make healthcare decisions for their loved ones. Caregivers will be randomly assigned to receive one of two different pamphlets to see how these materials might influence decision-making.Participants in the …
This study investigates the use of an investigational medication in children and adolescents with certain types of cancers that have come back or have not responded to treatment. These cancers include rhabdomyosarcoma (RMS), non-rhabdomyosarcoma soft tissue sarcoma (NRSTS), and Ewing sarcoma (EWS). The purpose is to assess the safety and …
