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Found 412 ctsi-central-admin trials

A listing of ctsi-central-admin medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Investigating the Safety of Intralesional Investigational Medication in Children with Advanced Growths

2 years - 21 years
All genders
This study investigates the safety of an investigational medication given directly into tumors in children with advanced solid tumors outside the brain. These tumors must be ones that can be directly injected. The purpose is to understand how the body responds to this treatment and to ensure it is safe …
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Investigating the Effectiveness of Investigational Medication for Non-Small Cell Lung Cancer

18 years - 100 years
All genders
This study investigates the effectiveness of an investigational medication compared to a placebo in treating patients with stage IB-IIIA non-small cell lung cancer (NSCLC) that has been completely removed by surgery. Non-small cell lung cancer is a type of lung cancer that grows and spreads more slowly than small cell …
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Investigation of Genetic Testing-Directed Treatment for Pediatric Tumors

1 years - 21 years
All genders
This study investigates how well treatment directed by genetic testing works in children with certain cancers like solid tumors, non-Hodgkin lymphomas, or histiocytic disorders. These are conditions where cells grow uncontrollably in different parts of the body. The study aims to find out if specific changes in genes can be …
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Investigational Medication for Memory and Thinking Problems in Parkinson's Disease Dementia

40 years - 85 years
All genders
This study investigates how an investigational medication compares with a placebo in treating memory and thinking problems in individuals with mild-to-moderate Parkinson's disease dementia. Parkinson's disease dementia (PDD) is a condition where people with Parkinson's disease experience a decline in cognitive functions, such as memory and thinking abilities, affecting their …
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Study on Investigational Medications for Glioma with BRAF V600 Mutation

1 years - 17 years
All genders
This study investigates the use of investigational medications in children and adolescents with a specific type of brain tumor called glioma. Glioma is a type of tumor that occurs in the brain and spinal cord. The study focuses on patients who have a BRAF V600 mutation, which is a change …
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Investigational Treatment Access for Blood Cancer Patients

100 years or below
All genders
This study investigates the use of an investigational treatment for patients with certain types of blood cancer, specifically acute lymphoblastic leukemia (ALL) and diffuse large B-cell lymphoma (DLBCL). These patients have a special need due to their leukapheresis product not meeting standard specifications. Leukapheresis is a procedure to collect blood …
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Investigating the Effectiveness of Investigational Medications in Treating Translocation Renal Cell Carcinoma

1 years - 100 years
All genders
This study investigates the effectiveness of a combination of two investigational medications, axitinib and nivolumab, in treating patients with a specific type of kidney cancer called TFE/translocation renal cell carcinoma. This type of cancer cannot be removed by surgery or has spread to other parts of the body. Axitinib is …
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Investigating Probiotics for Preventing Gastrointestinal Complications in Transplant Patients

2 years - 25 years
All genders
This study investigates whether the probiotic Lactobacillus plantarum can prevent gastrointestinal graft-versus-host disease (GI aGvHD) in children, adolescents, and young adults who are undergoing an alternative allogenic hematopoietic cell transplant (alloHCT). GI aGvHD is a condition where the donated cells attack the gastrointestinal tract of the recipient, causing inflammation and …
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Investigating Treatment for Stage IIIA Non-Small Cell Lung Cancer with Chemotherapy, Radiation, and Surgery

18 years - 100 years
All genders
This study investigates the treatment of Stage IIIA non-small cell lung cancer (NSCLC) using a combination of chemotherapy, radiation therapy, and surgery. NSCLC is a type of lung cancer that includes subtypes such as adenocarcinoma, squamous cell carcinoma, and large cell carcinoma. The study aims to understand the effectiveness of …
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Study of Investigational Medications in Advanced Solid Tumors

18 years - 100 years
All genders
This study investigates the effects of investigational medications in individuals with advanced or metastatic solid tumors. Advanced or metastatic solid tumors are cancers that have spread from their original location to other parts of the body. The study will examine the combination of two investigational drugs to assess their potential …
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