A listing of ctsi-central-admin medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
This study investigates the effectiveness of maintenance chemotherapy compared to observation in young patients with newly diagnosed ependymoma, a type of brain tumor. Ependymoma can be classified into different types, such as classic or anaplastic, which are determined by examining the tumor cells. The study aims to understand how well …
This study investigates whether training the pelvic floor muscles with a physical therapist before and after prostate surgery can improve the quality of life related to health after the surgery. The pelvic floor muscles support the bladder and bowel and help with urinary control. The study focuses on men undergoing …
The purpose of this study is to find out if music play activities can decrease distress and improve the quality of life for parents and young children during stem cell transplants for cancer. Stem cell transplant is a procedure used to replace damaged or destroyed bone marrow with healthy bone …
This study investigates a blood test called a "liquid biopsy" to find cancer cells in the blood of bladder cancer patients. Bladder cancer is a disease where cells in the bladder grow uncontrollably. This study aims to see if the test can reliably detect these cancer cells.The study uses a …
This study investigates an investigational medication in children with recurrent or refractory solid tumors, including tumors in the central nervous system (CNS). The purpose is to determine the highest dose that children can tolerate. The study will also look into how the medication affects the body, its side effects, and …
This study investigates the safety of an investigational medication in children who have solid tumors that have returned or are not responding to treatment. Solid tumors are abnormal masses of tissue that can occur in various parts of the body, including the brain and spinal cord, which are part of …
This study investigates how often cancer is found when an excisional biopsy is done near an initial core biopsy. The initial core biopsy showed flat epithelial atypia (FEA) or intraductal papilloma without atypia (IPWA). Flat epithelial atypia is a condition where the cells lining the milk ducts of the breast …
This study investigates the safety and effects of an investigational medication in children with high-grade gliomas, a type of brain tumor that is difficult to treat. High-grade gliomas are classified as WHO grade III or IV tumors, which are aggressive and fast-growing. The study focuses on pediatric patients who have …
This study investigates the effectiveness of adding low-dose oral methotrexate (MTX) to anti-TNF biological therapy in children with Crohn's disease. Anti-TNF therapy involves medications that block a protein called tumor necrosis factor, which can cause inflammation. The study aims to see if MTX helps maintain remission without the use of …
This study investigates the use of immunotherapy in treating patients with rare tumors. The purpose of this study is to evaluate how well the treatment works in patients with advanced rare cancers. Immunotherapy is a type of cancer treatment that helps the immune system fight cancer. In this study, patients …