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Found 199 Neoplasm trials

A listing of Neoplasm medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Study on Aspirin for Preventing Recurrence of HER2 Negative Breast Cancer

18 years - 69 years
All genders
This study investigates whether aspirin can help prevent the return of cancer in patients with HER2 negative breast cancer. HER2 is a protein that can affect the growth of cancer cells. This study focuses on patients who have already received treatments like chemotherapy, surgery, or radiation therapy.Participants will either receive …
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Investigating the Effectiveness of Investigational Medication Following Combined Modality Therapy in High Risk Anal Cancer

18 years - 100 years
All genders
This study investigates the effectiveness of an investigational medication following combined modality therapy in treating patients with high risk stage II-IIIB anal cancer. Anal cancer is a disease where malignant cells form in the tissues of the anus. The investigational medication is being studied to see if it can improve …
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Investigating the Effects of Regional Radiation Therapy in Low Risk Breast Cancer

40 years - 100 years
Female
This study investigates the effects of regional radiation therapy in patients with low risk breast cancer. The purpose is to compare the outcomes of those receiving usual care, which includes regional radiation therapy, with those not receiving this type of radiation. Researchers want to determine if skipping regional radiation therapy …
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Study on Investigational Medication for Vasomotor Symptoms

18 years - 70 years
Female
This study investigates the effectiveness of an investigational medication for treating Vasomotor Symptoms (VMS), which are hot flashes, compared to a placebo. Participants will be randomly assigned to one of two study arms: one receiving the investigational medication and the other receiving a placebo.During the study, participants will take either …
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Investigating the Safety and Effects of an Investigational Vaccine on Breast Cancer Recurrence

18 years - 100 years
All genders
This study investigates the safety of an investigational vaccine in patients with HER2 positive breast cancer. HER2 positive breast cancer is a type of breast cancer that tests positive for a protein called human epidermal growth factor receptor 2, which promotes the growth of cancer cells. The study also looks …
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Research Study on Radiation Therapy and Investigational Treatments for Cervical and Vaginal Cancer

18 years - 100 years
Female
This study investigates the effectiveness of adding an investigational medication to standard treatment for cervical and vaginal cancer. The study focuses on patients with certain stages of cervical or vaginal cancer that cannot be treated with surgery alone. The purpose is to see if the investigational medication, combined with radiation …
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Investigating Radiation Therapy with or without Investigational Medication for Inflammatory Breast Cancer

18 years - 100 years
All genders
This study investigates the effectiveness of radiation therapy with or without an investigational medication in treating patients with inflammatory breast cancer. Inflammatory breast cancer is a rare and aggressive form of breast cancer that spreads quickly. Radiation therapy uses high-energy x-rays to kill cancer cells and shrink tumors. The investigational …
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Investigating the Use of Investigational Medications in Breast Cancer Treatment

18 years - 100 years
All genders
Phase 2
This study investigates whether adding investigational medications to a treatment regimen can improve progression-free survival in patients with advanced HER2-positive breast cancer. HER2-positive breast cancer is a type of breast cancer that tests positive for a protein called human epidermal growth factor receptor 2, which promotes the growth of cancer …
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Investigating Treatment Sequences for Advanced Melanoma with BRAFV600 Mutation

18 years - 100 years
All genders
This study investigates treatments for patients with stage III-IV melanoma, which is a type of skin cancer that has spread and cannot be removed by surgery. The focus is on patients with a specific genetic change called the BRAFV600 mutation. The study aims to find out if starting treatment with …
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Investigating Hormone-Blocking Treatment Interruption and Breast Cancer Recurrence

18 years - 42 years
Female
This study investigates if taking a break from endocrine therapy to allow pregnancy affects the risk of breast cancer coming back. It focuses on young women who have had early breast cancer and are interested in becoming pregnant. Endocrine therapy involves using medicines that block certain hormones to slow or …
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