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Found 199 Neoplasm trials

A listing of Neoplasm medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Investigating the Effectiveness of Investigational Medication for Non-Small Cell Lung Cancer

18 years - 100 years
All genders
This study investigates the effectiveness of an investigational medication compared to a placebo in treating patients with stage IB-IIIA non-small cell lung cancer (NSCLC) that has been completely removed by surgery. Non-small cell lung cancer is a type of lung cancer that grows and spreads more slowly than small cell …
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Investigating Immunotherapy Continuation for Advanced Lung Cancer

18 years - 100 years
All genders
This study investigates the continuation of immunotherapy using an investigational medication following initial benefits from a PD-1 or PD-L1 inhibitor in patients with advanced lung cancer, specifically stage IV non-small cell lung cancer (NSCLC). The purpose is to see if this approach, combined with next-line chemotherapy, can extend the time …
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Investigating the Effects of Immunotherapy in Unresectable Stage III Non-Small Cell Lung Cancer

18 years - 100 years
All genders
This study investigates the effects of an investigational medication on patients with unresectable stage III non-small cell lung cancer (NSCLC). The purpose is to understand the benefits and side effects of using the investigational medication alone or in combination after patients have completed chemotherapy and radiation. NSCLC is a type …
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Investigating Treatment for Stage IIIA Non-Small Cell Lung Cancer with Chemotherapy, Radiation, and Surgery

18 years - 100 years
All genders
This study investigates the treatment of Stage IIIA non-small cell lung cancer (NSCLC) using a combination of chemotherapy, radiation therapy, and surgery. NSCLC is a type of lung cancer that includes subtypes such as adenocarcinoma, squamous cell carcinoma, and large cell carcinoma. The study aims to understand the effectiveness of …
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Study on Investigational Medication Combination with Chemotherapy for Small Cell Lung Cancer

18 years - 100 years
All genders
This study investigates the effectiveness of combining an investigational medication with carboplatin for treating small cell lung cancer. Small cell lung cancer is a type of cancer that usually starts in the breathing tubes and spreads quickly. The study aims to compare this combination to the usual treatment methods to …
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Investigating the Effectiveness of an Investigational Medication in ALK-Positive Lung Cancer

18 years - 100 years
All genders
This study investigates the effectiveness of an investigational medication compared to a placebo in treating patients with stage IB-IIIA non-small cell lung cancer (NSCLC) that has been surgically removed and has a mutation in the anaplastic lymphoma kinase (ALK) gene. ALK is a protein that, when altered, can contribute to …
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Investigation of Investigational Medication Therapy for Airway Plexiform Neurofibromas in Children with NF1

1 years - 12 years
All genders
This study investigates the effects of imatinib therapy on children with neurofibromatosis type 1 (NF1) who have airway-related plexiform neurofibromas. Plexiform neurofibromas are a type of tumor that can grow in various parts of the body, including the airway. The study aims to see if these specific tumors are more …
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Study of Immunotherapy in Treating Rare Tumors

18 years - 100 years
All genders
This study investigates the use of immunotherapy in treating patients with rare tumors. The purpose of this study is to evaluate how well the treatment works in patients with advanced rare cancers. Immunotherapy is a type of cancer treatment that helps the immune system fight cancer. In this study, patients …
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Study of Immune Cell Therapy for Advanced Skin Cancer

18 years - 70 years
All genders
This study investigates the use of adoptive cell therapy for patients with metastatic melanoma, a type of skin cancer that has spread to other parts of the body. The therapy involves using a patient's own immune cells, called tumor-infiltrating lymphocytes (TILs), to fight the cancer. Before receiving the TILs, patients …
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Investigation of Reduced-Dose Radiation Therapy for Oropharyngeal Cancer

18 years - 100 years
All genders
Phase 2/3
Interventional
This study investigates treatments for squamous cell carcinoma of the oropharynx, a type of throat cancer. The purpose is to compare different therapies using reduced-dose radiation. Participants will receive either radiation with cisplatin, a chemotherapy drug, or radiation with nivolumab, an immunotherapy drug.Participants will be randomly assigned to one of …
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