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Found 189 Neoplasm trials

A listing of Neoplasm medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Investigating Total Marrow Irradiation for Stem Cell Transplant Preparation

18 years - 65 years
All genders
This study investigates a new type of radiation therapy called total marrow irradiation (TMI) for patients undergoing allogeneic hematopoietic stem cell transplantation (Allo-HSCT). It aims to find the most effective dose of TMI when used with a chemotherapy drug called fludarabine. This combination is used to prepare patients for the …
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Investigational Treatment for Advanced Solid Tumors

18 years - 100 years
All genders
This study investigates an investigational medication given through a vein to adults with advanced solid tumors. These tumors are those that cannot be removed by surgery or have spread to other parts of the body and do not respond to standard treatments. The study aims to find the best dose …
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Investigation of Safety of Investigational Medications in Liver Cancer Treatment

18 years - 100 years
All genders
This study investigates the safety of two investigational medications in treating adults with liver cancer that cannot be removed by surgery. The medications are being tested alone and in combination to evaluate their effects on liver cancer, also known as hepatocellular carcinoma.Participants in this study will undergo treatment with either …
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Investigation of Genetic Testing-Directed Treatment for Pediatric Tumors

1 years - 21 years
All genders
This study investigates how well treatment directed by genetic testing works in children with certain cancers like solid tumors, non-Hodgkin lymphomas, or histiocytic disorders. These are conditions where cells grow uncontrollably in different parts of the body. The study aims to find out if specific changes in genes can be …
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Investigating Radiation Treatment Plans for Liver Cancer

18 years - 100 years
All genders
The purpose of this study is to compare different radiation treatment plans for patients with liver cancer, such as hepatocellular carcinoma or cholangiocarcinoma. This study investigates whether adding specific imaging scans can help reduce radiation exposure to healthy liver tissue. A routine treatment plan will be compared with a plan …
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Study on the Effects of Investigational Medication with Radioembolization (a procedure using tiny radioactive beads to target cancer cells in the liver) for Liver Cancer

18 years - 100 years
All genders
This study investigates the effects of an investigational medication combined with Yttrium-90 radioembolization for patients with advanced liver cancer, specifically hepatocellular carcinoma. This type of cancer affects the liver and is considered advanced when it cannot be treated with surgery or liver transplant. The study aims to understand how well …
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Study on Radioembolization Therapy for Liver Disease

18 years - 100 years
All genders
This study investigates the safety of radioembolization therapy using Yttrium 90 for treating liver disease. Radioembolization is a procedure that delivers radiation directly to the liver to target cancer cells, specifically for hepatocellular carcinoma (HCC).Participants will undergo various procedures related to the therapy, including pre-treatment, during treatment, and post-treatment evaluations. …
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Study of Accelerated vs. Standard Chemotherapy for Metastatic Germ Cell Tumors

11 years - 45 years
All genders
This study investigates the effectiveness of an accelerated chemotherapy regimen compared to the standard regimen for treating metastatic germ cell tumors (GCTs). Germ cell tumors are a type of cancer that begins in the cells that form sperm or eggs. The study aims to see if the accelerated treatment is …
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Study on Investigational Medication for Germ Cell Tumors

18 years - 100 years
Male
This study investigates the effectiveness of an investigational medication for treating germ cell tumors that do not respond to platinum-based treatments. Germ cell tumors are a type of cancer that begins in the cells that develop into sperm or eggs. The purpose of the study is to find the best …
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Investigating Chemotherapy Options for Germ Cell Tumors

49 years or below
All genders
This study investigates the effects of different chemotherapy drugs on patients with germ cell tumors, which are a type of cancer that can occur in the ovaries, testicles, or other areas. The purpose is to compare carboplatin and cisplatin to determine which is more effective for patients with standard risk …
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