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Found 189 Neoplasm trials

A listing of Neoplasm medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Research Study on Observation vs. Radiation Therapy After Surgery for Grade II Meningioma

18 years - 100 years
All genders
Phase 3
Interventional
This study investigates the effects of two different approaches after surgery for grade II meningioma, a type of brain tumor. The purpose of this study is to compare the outcomes of observation alone versus radiation therapy following surgery. Participants will be randomly assigned to either continue with observation or receive …
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Study of Investigational Medication for Children with Cancer

1 years - 17 years
All genders
This study investigates an investigational medication to understand its safety, tolerability, and effects on tumors in children with cancer. The purpose is to determine the highest dose that can be given safely without causing serious side effects. The study will also examine how the medication is absorbed and broken down …
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Investigating Methods to Increase Cancer Screening Rates in Rural Women

50 years - 74 years
Female
This study investigates different methods to increase screening rates for Breast Cancer, Cervical Cancer, and Colorectal Cancer among women aged 50 to 74 living in rural areas. The study compares the use of a tailored interactive DVD (TIDVD), a combination of telephone patient navigation and TIDVD, and usual care to …
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Investigating the Effects of an Investigational Medication with or without an Additional Agent in Treating Solid Tumors That Have Returned or Are Resistant to Treatment in Younger Patients

1 years - 30 years
All genders
This study investigates the effects of an investigational medication, given with or without an additional agent, on younger patients with solid tumors or sarcomas that have either returned after treatment or do not respond to treatment. Solid tumors are masses of tissue that can occur in various parts of the …
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Radiation and Chemotherapy for Vulvar Cancer

18 years - 100 years
Female
This study investigates the use of radiation therapy combined with chemotherapy drugs, gemcitabine hydrochloride and cisplatin, in treating patients with locally advanced squamous cell carcinoma of the vulva. Squamous cell carcinoma is a type of skin cancer that can develop in various parts of the body, including the vulva. The …
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Investigating Treatments for Hormone-Sensitive Prostate Cancer

18 years - 100 years
Male
This study investigates treatments for hormone-sensitive prostate cancer that has spread to other parts of the body. The purpose is to see if adding cabazitaxel to abiraterone acetate and antiandrogen therapy can improve progression-free survival in patients who have already been treated with docetaxel and androgen deprivation therapy. Hormone-sensitive prostate …
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Study on the Safety of an Investigational Medication for Blood Cancers

18 years - 100 years
All genders
This study investigates the effectiveness, safety, and tolerability of an investigational medication for patients with relapsed or refractory blood cancers, which are also known as hematologic malignancies. These are cancers that affect the blood, bone marrow, and lymph nodes. The study aims to understand how well the medication works and …
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Program with 6 clinical trials

Cancer Drug Development Program

Develop a new cancer drug targeting multiple types of tumors.
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Investigation of Investigational Medication in Treating Rare Tumors in Young Patients

2 years - 30 years
All genders
This study investigates how well an investigational medication works in treating young patients with sarcomas, Wilms tumor, or other rare tumors. These tumors may have returned, not responded to therapy, or been newly diagnosed. The purpose is to determine the rate at which these tumors respond to the investigational medication.Participants …
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Study on Combination Chemotherapy with Investigational Medication for Stage III Colon Cancer

18 years - 100 years
All genders
This study investigates the effectiveness of combination chemotherapy with an investigational medication compared to chemotherapy alone in patients with stage III colon cancer. The focus is on patients with a specific condition called deficient DNA mismatch repair (dMMR), which is when the body's natural ability to fix DNA mistakes is …
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