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Found 189 Neoplasm trials

A listing of Neoplasm medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Study on Investigational Medication Combination with Chemotherapy for Small Cell Lung Cancer

18 years - 100 years
All genders
This study investigates the effectiveness of combining an investigational medication with carboplatin for treating small cell lung cancer. Small cell lung cancer is a type of cancer that usually starts in the breathing tubes and spreads quickly. The study aims to compare this combination to the usual treatment methods to …
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Investigating the Effectiveness of an Investigational Medication in ALK-Positive Lung Cancer

18 years - 100 years
All genders
This study investigates the effectiveness of an investigational medication compared to a placebo in treating patients with stage IB-IIIA non-small cell lung cancer (NSCLC) that has been surgically removed and has a mutation in the anaplastic lymphoma kinase (ALK) gene. ALK is a protein that, when altered, can contribute to …
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Investigation of Reduced-Dose Radiation Therapy for Oropharyngeal Cancer

18 years - 100 years
All genders
Phase 2/3
Interventional
This study investigates treatments for squamous cell carcinoma of the oropharynx, a type of throat cancer. The purpose is to compare different therapies using reduced-dose radiation. Participants will receive either radiation with cisplatin, a chemotherapy drug, or radiation with nivolumab, an immunotherapy drug.Participants will be randomly assigned to one of …
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Investigating Immunotherapy in Small Cell Lung Cancer Treatment

18 years - 100 years
All genders
Phase 2/3
Interventional
This study investigates whether adding an investigational immunotherapy medication to the usual treatment can reduce the chance of small cell lung cancer growing or spreading. Small cell lung cancer is a type of cancer that starts in the lungs and can quickly spread to other parts of the body. The …
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Study on Gene Changes During Lung Cancer Treatment

18 years - 100 years
Accepts healthy volunteer
All genders
This study investigates how certain biomarkers, which are signs in your genes that indicate how well your body responds to treatment, change before, during, and after standard care for non-small cell lung cancer (NSCLC). The purpose of this study is to better understand the genetic changes that occur over the …
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Study on Detecting Cancer DNA in Blood and Urine

18 years - 100 years
All genders
This study investigates a new test that aims to detect small pieces of cancer DNA in blood and urine. Cancer DNA, or ctDNA, refers to the genetic material released by cancer cells into the bloodstream. This study looks to improve the detection of ctDNA compared to current methods.Participants in the …
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Investigating Radiation Dosage for Lung Cancer Treatment

18 years - 100 years
All genders
This study investigates whether a specific type of radiation therapy, called stereotactic ablative body radiation (SABR), is safe and effective for treating early-stage squamous cell carcinoma of the lung. Squamous cell carcinoma is a kind of lung cancer that starts in the flat cells lining the lungs. The study aims …
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Investigating Timing of Partial Breast Irradiation and Chemotherapy (Cancer Treatment)

18 years - 100 years
Female
This study investigates the effects of giving partial breast irradiation and chemotherapy at the same time compared to giving them at different times for women with breast cancer. Breast cancer can be categorized by hormone receptor status, such as estrogen receptor (ER) negative or positive. Previous studies have shown that …
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Investigating the Safety and Side Effects of Combining Investigational Medication with Radiation for Breast Cancer

18 years - 100 years
Female
This study investigates the safety and side effects of combining an investigational medication with radiation for treating women with breast cancer. Specifically, it focuses on women who still have cancer in their breast or underarm lymph nodes after receiving chemotherapy before surgery. The study aims to find out how many …
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Study on Pre-surgical Treatment for Muscle Invasive Bladder Cancer

18 years - 100 years
All genders
This study investigates treatments for muscle invasive bladder cancer, which is a type of cancer affecting the bladder muscle. The purpose is to explore the effects of different treatments before surgery in patients who are candidates for neoadjuvant therapy. Neoadjuvant therapy is treatment given before the main treatment, which is …
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