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Found 204 Neoplasms trials

A listing of Neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Study on Whole Brain Radiation Therapy (WBRT) for Brain Tumors

18 - 100
All genders
This study investigates the effects of whole brain radiation therapy (WBRT) combined with a higher dose of radiation targeted at individual brain tumors. Researchers want to understand how this treatment impacts tumor control, memory, and specific thought processes. WBRT is a treatment that uses radiation to target the entire brain, …
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Investigating an Antibody Treatment for Early Alzheimer's Disease

50 - 90
All genders
Phase 3
This study investigates an investigational medication for people with early Alzheimer's Disease (AD), which includes mild cognitive impairment or mild dementia. AD is marked by a build-up of an abnormal protein called amyloid in the brain, which can affect memory and thinking. The investigational medication is a monoclonal antibody, meaning …
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Investigating Treatment Effects of an Investigational Antibody in Pediatric Neuroblastoma

18 or below
All genders
This study investigates the effects of an investigational antibody treatment for children with a type of cancer called neuroblastoma that has spread to the brain or the lining of the brain and spinal cord. Neuroblastoma is a cancer that starts in young nerve cells and can spread to other parts …
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Study on the Safety of an Investigational Medication in Children with Tumors that Have Returned

1 - 21
All genders
This study investigates the safety of an investigational medication in children who have solid tumors that have returned or are not responding to treatment. Solid tumors are abnormal masses of tissue that can occur in various parts of the body, including the brain and spinal cord, which are part of …
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Research Study on an Investigational Medication in Children with Recurrent or Refractory Solid Tumors

1 - 21
All genders
This study investigates an investigational medication in children with recurrent or refractory solid tumors, including tumors in the central nervous system (CNS). The purpose is to determine the highest dose that children can tolerate. The study will also look into how the medication affects the body, its side effects, and …
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Investigating the Safety and Dosage of an Investigational Medication with Chemotherapy in Pediatric Solid Tumors

1 - 21
All genders
This study investigates the safety and best dose of an investigational medication given with chemotherapy drugs, temozolomide and irinotecan, in children with solid tumors that have returned or not responded to treatment. Solid tumors are growths of abnormal cells that can occur in various parts of the body. This study …
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Study on Investigational Medication Combination for Pediatric Tumors

2 - 21
All genders
This study investigates the effects of a combination of investigational medications on pediatric subjects with certain types of recurrent or refractory solid tumors. The purpose is to find the highest safe dose of these medications when given together, and to understand how the body processes them. Additionally, researchers will study …
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Study on Detecting Cancer DNA in Blood and Urine

18 - 100
All genders
This study investigates a new test that aims to detect small pieces of cancer DNA in blood and urine. Cancer DNA, or ctDNA, refers to the genetic material released by cancer cells into the bloodstream. This study looks to improve the detection of ctDNA compared to current methods.Participants in the …
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Investigating the Effects of an Investigational Medication for Advanced Solid Tumors with KRAS Mutation

18 - 100
All genders
This study investigates the effects of an investigational medication for treating advanced solid tumors with a specific KRAS mutation. These are tumors that have a change in the KRAS gene, which can cause cancer cells to grow. The study is in Phase 1, which means it is the first time …
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Study of Investigational Medications in Advanced Solid Tumors

18 - 100
All genders
This study investigates the effects of investigational medications in individuals with advanced or metastatic solid tumors. Advanced or metastatic solid tumors are cancers that have spread from their original location to other parts of the body. The study will examine the combination of two investigational drugs to assess their potential …
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